3-NITRO-4-(TRIFLUOROMETHOXY)ANILINE

Base Information

• Chemical Name: 3-NITRO-4-(TRIFLUOROMETHOXY)ANILINE
• CAS No.: 2822-50-6
• Molecular Formula: C7H5F3N2O3
• Molecular Weight: 222.124
• Hs Code.: 2922299090
• Mol file: 2822-50-6.mol

Synonyms:p-Anisidine,a,a,a-trifluoro-3-nitro- (6CI,8CI);3-Nitro-4-(trifluoromethoxy)aniline;

Chemical Property of 3-NITRO-4-(TRIFLUOROMETHOXY)ANILINE

Chemical Property:

• Vapor Pressure: 0.00115mmHg at 25°C
• Refractive Index: 1.525
• Boiling Point: 300.09 °C at 760 mmHg
• Flash Point: 135.29 °C
• PSA: 81.07000
• Density: 1.543 g/cm³
• LogP: 3.18000

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Nitro-4-(trifluoromethoxy)aniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-NITRO-4-(TRIFLUOROMETHOXY)ANILINE

There total 2 articles about 3-NITRO-4-(TRIFLUOROMETHOXY)ANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4-(trifluoromethoxy)aniline (461-82-5) → 3-nitro-4-(trifluoromethoxy)aniline (2822-50-6)

Guidance literature:

With sulfuric acid; uronium nitrate; In water; at 0 - 10 ℃; for 0.166667h;

Reference yield:

→ 3-nitro-4-(trifluoromethoxy)aniline (2822-50-6)

Guidance literature:

4-Amino-1-trifluormethoxy-benzol, 1. Loesen in H2SO4 unterhalb 40grad, 2. 93percentig. HNO3 u. H2SO4 (D: 1.83), 0grad;

Reference yield: 100.0%

3-nitro-4-(trifluoromethoxy)aniline (2822-50-6) → 4-trifluoromethoxybenzene-1,3-diamine (873055-90-4)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethyl acetate; Inert atmosphere;

upstream raw materials:

4-(trifluoromethoxy)aniline

Downstream raw materials:

4-trifluoromethoxybenzene-1,3-diamine

Refernces

• 1、 -. "CARBONYL-AMINO SUBSTITUTED ACYL PHENYL UREA DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF". Page/Page column 32. . Retrieved 2008/06/13.