2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL

Base Information

• Chemical Name: 2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL
• CAS No.: 56456-51-0
• Molecular Formula: C8H6ClF3O
• Molecular Weight: 210.583
• Hs Code.: 2906299090
• Mol file: 56456-51-0.mol

Synonyms:2-Chloro-4-(trifluoromethyl)benzylalcohol;

Chemical Property of 2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL

Chemical Property:

• Melting Point: 50-52℃
• Boiling Point: 226.5 °C at 760 mmHg
• Flash Point: 90.8 °C
• PSA: 20.23000
• Density: 1.416 g/cm³
• LogP: 2.85110
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Chloro-4-(trifluoromethyl)benzylalcohol ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Chloro-4-(trifluoromethyl)benzylalcohol

Technology Process of 2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL

There total 1 articles about 2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-chloro-4-(trifluoromethyl)benzoic acid (23228-45-7) → (2-chloro-4-(trifluoromethyl)phenyl)methanol (56456-51-0)

Guidance literature:

With borane-THF; at 0 - 30 ℃; for 1h;

Reference yield: 99.0%

(2-chloro-4-(trifluoromethyl)phenyl)methanol (56456-51-0) → 1-(bromomethyl)-2-chloro-4-(trifluoromethyl)benzene (279252-26-5)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; at 0 - 30 ℃; for 2h;

Reference yield: 99.0%

(2-chloro-4-(trifluoromethyl)phenyl)methanol (56456-51-0) + carbon tetrabromide (558-13-4) → 1-(bromomethyl)-2-chloro-4-(trifluoromethyl)benzene (279252-26-5)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; diethyl ether; hexane;

upstream raw materials:

2-chloro-4-(trifluoromethyl)benzoic acid

Downstream raw materials:

1-(bromomethyl)-2-chloro-4-(trifluoromethyl)benzene

2-chloro-1-((methanesulfonyloxy)methyl)-4-(trifluoromethyl)benzene

2-chloro-1-(chloromethyl)-4-(trifluoromethyl)benzene

2-chloro-4-(trifluoromethyl)-benzaldehyde

Refernces

• 1、 -. "ARYLALKANOIC ACID DERIVATIVE". . . Retrieved 2008/06/13.