Technology Process of C31H44N4O12S2
There total 4 articles about C31H44N4O12S2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Ac-Glu-[Cys(StBu)-Gly-OH]-OMe;
With
TEA; isobutyl chloroformate;
In
N,N-dimethyl-formamide;
at -15 ℃;
for 0.25h;
(+)-3,4-diacetyloxy-L-phenylalanine methyl ester hydrochloride;
In
N,N-dimethyl-formamide;
at 0 - 5 ℃;
for 19h;
Further stages.;
DOI:10.1021/jm070037v
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 92 percent / DCC / tetrahydrofuran / 19 h / 0 - 5 °C
2.1: TFA / 2 h / 20 °C
3.1: TEA; isobutyl chloroformate / dimethylformamide / 0.25 h / -15 °C
3.2: dimethylformamide / 19 h / 0 - 5 °C
With
TEA; dicyclohexyl-carbodiimide; trifluoroacetic acid; isobutyl chloroformate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm070037v
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: TFA / 2 h / 20 °C
2.1: TEA; isobutyl chloroformate / dimethylformamide / 0.25 h / -15 °C
2.2: dimethylformamide / 19 h / 0 - 5 °C
With
TEA; trifluoroacetic acid; isobutyl chloroformate;
In
N,N-dimethyl-formamide;
DOI:10.1021/jm070037v