Technology Process of 5-(3-bromophenyl)benzo[b]naphtho[2,1-d]furan
There total 6 articles about 5-(3-bromophenyl)benzo[b]naphtho[2,1-d]furan which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
water; toluene;
for 8h;
Inert atmosphere;
Reflux;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: toluene-4-sulfonic acid / toluene / 24 h / Reflux
2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,4-dioxane / 12 h / Inert atmosphere; Reflux
3.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 5 h / 60 °C
4.1: n-butyllithium / hexane; tetrahydrofuran / 2 h / -78 - 0 °C
4.2: 5.17 h / -78 - 20 °C
4.3: 1 h / 20 °C
5.1: sodium carbonate / tetrakis(triphenylphosphine) palladium(0) / toluene; water / 8 h / Inert atmosphere; Reflux
With
N-Bromosuccinimide; n-butyllithium; sodium carbonate; toluene-4-sulfonic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; 1,4-dioxane; hexane; water; N,N-dimethyl-formamide; toluene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: toluene-4-sulfonic acid / toluene / 24 h / Reflux
2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,4-dioxane / 12 h / Inert atmosphere; Reflux
3.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 5 h / 60 °C
4.1: n-butyllithium / hexane; tetrahydrofuran / 2 h / -78 - 0 °C
4.2: 5.17 h / -78 - 20 °C
4.3: 1 h / 20 °C
5.1: sodium carbonate / tetrakis(triphenylphosphine) palladium(0) / toluene; water / 8 h / Inert atmosphere; Reflux
With
N-Bromosuccinimide; n-butyllithium; sodium carbonate; toluene-4-sulfonic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; 1,4-dioxane; hexane; water; N,N-dimethyl-formamide; toluene;