N-Cbz-N-methyl-L-leucine

Base Information Edit

Chemical Name:N-Cbz-N-methyl-L-leucine
CAS No.:33099-08-0
Molecular Formula:C15H21NO4
Molecular Weight:279.336
Hs Code.:2922509090
DSSTox Substance ID:DTXSID50426670
Nikkaji Number:J494.843B
Wikidata:Q72516286
Mol file:33099-08-0.mol

Synonyms:33099-08-0;N-Cbz-N-methyl-L-leucine;Z-N-Me-Leu-OH;Cbz-N-methyl-L-leucine;Z-N-methyl-L-leucine;(2S)-4-methyl-2-[methyl(phenylmethoxycarbonyl)amino]pentanoic acid;(S)-2-(((Benzyloxy)carbonyl)(methyl)amino)-4-methylpentanoic acid;Z-MeLeu-OH;Z-N-a-methyl-L-Leucine;Z-N-|A-methyl-L-Leucine;Z-L-MeLeu-OH;Cbz-N-Methyl-L-Leu-OH;N-Methyl-N-Cbz-L-leucine;N-Methyl-N-[(phenylmethoxy)carbonyl]-L-leucine;SCHEMBL2300007;DTXSID50426670;TVXSGOBGRXNJLM-ZDUSSCGKSA-N;MFCD00038521;AKOS015890053;Z-N-Me-Leu-OH, >=98.0%;CS-W012283;FD21864;HY-W011567;DS-16201;Benzyloxycarbonyl-N-alpha-methyl-L-leucine;N-((Benzyloxy)carbonyl)-N-methyl-L-leucine;EN300-6748037;(S)-2-((benzyloxycarbonyl)(methyl)amino)-4-methylpentanoic acid;(2S)-2-{[(BENZYLOXY)CARBONYL](METHYL)AMINO}-4-METHYLPENTANOIC ACID

Suppliers and Price of N-Cbz-N-methyl-L-leucine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Z-N-methyl-L-leucine 99+%
1g
$ 200.00

Usbiological
Z-N-methyl-L-leucine
1g
$ 346.00

TRC
(S)-2-(((Benzyloxy)carbonyl)(methyl)amino)-4-methylpentanoicAcid
500mg
$ 65.00

TRC
(S)-2-(((Benzyloxy)carbonyl)(methyl)amino)-4-methylpentanoicAcid
250mg
$ 55.00

TRC
(S)-2-(((Benzyloxy)carbonyl)(methyl)amino)-4-methylpentanoicAcid
100mg
$ 45.00

Iris Biotech GmbH
Z-L-MeLeu-OH
5 g
$ 303.75

Iris Biotech GmbH
Z-L-MeLeu-OH
1 g
$ 94.50

chempep
Z-N-Me-L-Leu-OH
5g
$ 200.00

chempep
Z-N-Me-L-Leu-OH
25g
$ 640.00

Chem-Impex
Z-N-methyl-L-leucine,99%(HPLC) 99%(HPLC)
100G
$ 2255.68

Total 41 raw suppliers

Chemical Property of N-Cbz-N-methyl-L-leucine Edit

Chemical Property:

Vapor Pressure:8.72E-08mmHg at 25°C
Melting Point:74-75 °C
Refractive Index:1.528
Boiling Point:419.449 °C at 760 mmHg
PKA:4.02±0.21(Predicted)
Flash Point:207.475 °C
PSA：66.84000
Density:1.145 g/cm³
LogP:2.75430
Storage Temp.:-15°C
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:279.14705815
Heavy Atom Count:20
Complexity:324

Purity/Quality:: Z-N-methyl-L-leucine 99+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)O)N(C)C(=O)OCC1=CC=CC=C1
Isomeric SMILES:CC(C)C[C@@H](C(=O)O)N(C)C(=O)OCC1=CC=CC=C1

Technology Process of N-Cbz-N-methyl-L-leucine

There total 9 articles about N-Cbz-N-methyl-L-leucine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 66866-66-8
phenylmethyl (4S)-4-(2-methylpropyl)-5-oxo-1,3-oxazolidine-3-carboxylate

: 33099-08-0
N-benzyloxycarbonyl-N-methyl-L-leucine

Guidance literature:: With chloro-trimethyl-silane; sodium cyanoborohydride; In acetonitrile; for 0.166667h; Ambient temperature;
DOI:10.1246/cl.1999.299

Reference yield: 96.0%

: 2018-66-8
Z-Leu-OH

: 77-78-1
dimethyl sulfate

: 33099-08-0
N-benzyloxycarbonyl-N-methyl-L-leucine

Guidance literature:: With potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In tetrahydrofuran; for 0.5h; Ambient temperature;
DOI:10.1016/S0040-4020(98)01042-4