7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid

Base Information

• Chemical Name: 7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid
• CAS No.: 127582-76-7
• Molecular Formula: C22H25 N O4
• Molecular Weight: 367.44
• Hs Code.: 2924299090
• European Community (EC) Number: 807-074-0
• DSSTox Substance ID: DTXSID30925914
• Wikidata: Q82900340
• Mol file: 127582-76-7.mol

Synonyms:127582-76-7;Fmoc-7-Ahp-OH;Fmoc-7-aminoheptanoic acid;Fmoc-7-amino-heptanoic acid;7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid;7-(9H-fluoren-9-ylmethoxycarbonylamino)heptanoic Acid;Heptanoic acid, 7-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-;MFCD01861353;fmoc-ahp(7)-oh;7-(Fmoc-amino)enanthic acid;7-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)heptanoic acid;Fmoc-7-Aminoheptanoicacid;N-Fmoc-7-aminoheptanoic Acid;SCHEMBL178890;DTXSID30925914;FRPYXTFBPCYALT-UHFFFAOYSA-N;AKOS012614414;AM82453;CS-W009772;BP-28253;DS-18376;SY034528;Fmoc-7-Ahp-OH, >=98.0% (HPLC);FT-0679731;D70804;EN300-650280;A889178;J-005508;Z1123720013;7-(((9H-fluoren-9-yl)methoxy)carbonylamino)heptanoic acid;7-({[(9H-Fluoren-9-yl)methoxy](hydroxy)methylidene}amino)heptanoic acid

Chemical Property of 7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid

Chemical Property:

• Vapor Pressure: 9.12E-15mmHg at 25°C
• Boiling Point: 590oC at 760 mmHg
• PKA: 4.77±0.10(Predicted)
• Flash Point: 310.6oC
• PSA: 75.63000
• Density: 1.191g/cm3
• LogP: 4.95110
• Storage Temp.: 2-8°C
• Water Solubility.: Slightly soluble in water.
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 10
• Exact Mass: 367.17835828
• Heavy Atom Count: 27
• Complexity: 473

Purity/Quality:

98%,99%, ^*data from raw suppliers

Fmoc-7-amino-heptanoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCCCCCC(=O)O
• Description: Fmoc-7-amino-heptanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
• Uses: 7-(Fmoc-amino)heptanoic acid is used as pharmaceutical intermediates.