C₃₆H₄₇N₆O₁₃PS

Base Information

• Chemical Name: C₃₆H₄₇N₆O₁₃PS
• CAS No.: 1608113-72-9
• Molecular Formula: C₃₆H₄₇N₆O₁₃PS
• Molecular Weight: 834.841
• Mol file: 1608113-72-9.mol

Synonyms:C₃₆H₄₇N₆O₁₃PS

Chemical Property of C₃₆H₄₇N₆O₁₃PS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₆H₄₇N₆O₁₃PS

There total 14 articles about C₃₆H₄₇N₆O₁₃PS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

N-For-Met-L-Glu-NH2 (1608114-23-3) + C25H30N3O9P (1608113-70-7) → C36H47N6O13PS (1608113-72-9)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide; at 0 - 20 ℃; for 24h; Inert atmosphere;

DOI:10.1002/ejoc.201301781

Reference yield:

benzyl L-γ-glutamate α-amide trifluoroacetic acid salt → C36H47N6O13PS (1608113-72-9)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydrogencarbonate / tetrahydrofuran; water / 16 h / 0 - 20 °C / Inert atmosphere

2: palladium 10% on activated carbon; hydrogen / ethanol / 16 h / 0 - 20 °C / 760.05 Torr

3: dmap; dicyclohexyl-carbodiimide / dichloromethane; N,N-dimethyl-formamide / 24 h / 0 - 20 °C / Inert atmosphere

With dmap; palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In tetrahydrofuran; ethanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1002/ejoc.201301781

Reference yield:

benzyl N-tert-butyloxycarbonyl-L-γ-glutamate α-amide (18800-73-2) → C36H47N6O13PS (1608113-72-9)

Guidance literature:

Multi-step reaction with 4 steps

1: methyl-phenyl-thioether / dichloromethane

2: sodium hydrogencarbonate / tetrahydrofuran; water / 16 h / 0 - 20 °C / Inert atmosphere

3: palladium 10% on activated carbon; hydrogen / ethanol / 16 h / 0 - 20 °C / 760.05 Torr

4: dmap; dicyclohexyl-carbodiimide / dichloromethane; N,N-dimethyl-formamide / 24 h / 0 - 20 °C / Inert atmosphere

With dmap; methyl-phenyl-thioether; palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In tetrahydrofuran; ethanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1002/ejoc.201301781

upstream raw materials:

N-formyl-methionine-succinimidyl ester

benzyl N-tert-butyloxycarbonyl-L-γ-glutamate α-amide

N-For-Met-L-Glu-NH₂

C₂₅H₃₀N₃O₉P

Refernces