DL-3-(1-NAPHTHYL)ALANINE

Base Information

• Chemical Name: DL-3-(1-NAPHTHYL)ALANINE
• CAS No.: 28095-56-9
• Molecular Formula: C13H13NO2
• Molecular Weight: 215.252
• Hs Code.: 2922499990
• Mol file: 28095-56-9.mol

Synonyms:3-naphthalen-1-ylalanine;1-Naphthalenealanine;1-Naphthalenepropanoic acid, α-amino-;2-Amino-3-(1-naphthalenyl)propanoic acid;2-Amino-3-(1-naphthyl)propanoic acid;2-amino-3-naphthalen-1-ylpropanoic acid;3-(1-Naphthyl)alanine;D,L-β-(1-Naphthyl)alanine;

Chemical Property of DL-3-(1-NAPHTHYL)ALANINE

Chemical Property:

• Vapor Pressure: 1.54E-07mmHg at 25°C
• Melting Point: 239℃
• Refractive Index: 1.66
• Boiling Point: 412.3 °C at 760 mmHg
• PKA: 2.21±0.30(Predicted)
• Flash Point: 203.2 °C
• PSA: 63.32000
• Density: 1.254 g/cm³
• LogP: 2.49450
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-(1-Naphthyl)-DL-alanine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DL-3-(1-NAPHTHYL)ALANINE

There total 18 articles about DL-3-(1-NAPHTHYL)ALANINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C21H15N3O3(2-)*Ni(2+) + 2-bromomethylnaphthyl bromide (939-26-4) → 2-amino-3-(1-naphthyl)propanoic acid (28095-56-9,68798-79-8,7758-42-1)

Guidance literature:

With potassium hydroxide; C-2; In dichloromethane; at 20 ℃;

DOI:10.1007/BF00959641

Reference yield:

4-naphthalen-1-ylmethylene-2-phenyl-4H-oxazol-5-one (57427-83-5,57427-99-3,58130-84-0) → 2-amino-3-(1-naphthyl)propanoic acid (28095-56-9,68798-79-8,7758-42-1)

Guidance literature:

With phosphorus; acetic anhydride; anschliessend Behandeln mit wss. HI;

Reference yield:

1-Chloromethylnaphthalene (86-52-2) → 2-amino-3-(1-naphthyl)propanoic acid (28095-56-9,68798-79-8,7758-42-1)

Guidance literature:

With diethyl acetylaminomalonate; ethanol; sodium ethanolate; Erhitzen des Reaktionsprodukts mit wss. Bromwasserstoffsaeure;

upstream raw materials:

4-naphthalen-1-ylmethylene-2-phenyl-4H-oxazol-5-one

5-[1]naphthylmethylene-3-p-tolyl-imidazolidine-2,4-dione

2-benzoylamino-3-naphthalen-1-yl-propionic acid

acetylamino-[1]naphthylmethyl-malonic acid

Downstream raw materials:

3-(naphthalene-1-yl)-2-oxopropanoic acid

L-1-naphthylalanine

3-(1-naphthyl)-D-alanine

naphythylalanine methylester

Refernces

• 1、 -. "Benzo-fused lactams". . . Retrieved 2008/06/13.
• 2、 -. "COMPOUNDS CONTAINING A FUSED BICYCLE RING AND PROCESSES THEREFOR". . . Retrieved 2008/06/13.