(E)-1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decen-1-yl)-4-methoxybenzene

Base Information

• Chemical Name: (E)-1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decen-1-yl)-4-methoxybenzene
• CAS No.: 1423439-31-9
• Molecular Formula: C₁₇H₉F₁₇O
• Molecular Weight: 552.231
• Mol file: 1423439-31-9.mol

Synonyms:(E)-1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decen-1-yl)-4-methoxybenzene

Chemical Property of (E)-1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decen-1-yl)-4-methoxybenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decen-1-yl)-4-methoxybenzene

There total 3 articles about (E)-1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decen-1-yl)-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1-iodoheptadecafluorooctane (507-63-1) + 3-(4'-methoxyphenyl)propenoic acid (830-09-1) → (E)-1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decen-1-yl)-4-methoxybenzene (1423439-31-9)

Guidance literature:

With [2,2]bipyridinyl; copper(I) trifluoromethanesolfonate toluene complex; Dimethyl phosphite; In acetonitrile; at 80 ℃; for 72h; stereoselective reaction; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.6b02613

Reference yield: 78.0%

1-perfluorooctyl bromide (423-55-2) + 3-(4'-methoxyphenyl)propenoic acid (830-09-1) → (E)-1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decen-1-yl)-4-methoxybenzene (1423439-31-9)

Guidance literature:

With [2,2]bipyridinyl; copper(I) trifluoromethanesolfonate toluene complex; Dimethyl phosphite; In acetonitrile; at 80 ℃; for 72h; stereoselective reaction; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.6b02613

Reference yield:

1-bromo-4-methoxy-benzene (104-92-7) + 1H,1H,2H-perfluorodecene (21652-58-4) → (E)-1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decen-1-yl)-4-methoxybenzene (1423439-31-9) + C17H9F17O (1423439-60-4)

Guidance literature:

With potassium phosphate; C₃₀H₂₅ClN₂P₂Pd; In N,N-dimethyl-formamide; at 130 ℃; for 72h; Overall yield = 50 %; Sealed tube;

DOI:10.1016/j.jfluchem.2012.12.009

upstream raw materials:

1-bromo-4-methoxy-benzene

1H,1H,2H-perfluorodecene

1-iodoheptadecafluorooctane

3-(4'-methoxyphenyl)propenoic acid

Refernces

• 1、 Feng, Jie,Cai, Chun. "An efficient synthesis of perfluoroalkenylated aryl compounds via Pincer-Pd catalyzed Heck couplings". . p. 6 - 10. Retrieved 2013/03/28.