Trolamine salicylate

Base Information

• Chemical Name: Trolamine salicylate
• CAS No.: 2174-16-5
• Deprecated CAS: 7376-33-2,99-01-4,8014-28-6,8014-28-6,99-01-4
• Molecular Formula: C13H21NO6
• Molecular Weight: 287.313
• Hs Code.: 29225000
• European Community (EC) Number: 218-531-3
• UNII: H8O4040BHD
• DSSTox Substance ID: DTXSID4047969
• Wikipedia: Trolamine_salicylate
• Wikidata: Q7845153
• NCI Thesaurus Code: C84231
• RXCUI: 38866
• Metabolomics Workbench ID: 152436
• ChEMBL ID: CHEMBL2107288
• Mol file: 2174-16-5.mol

Synonyms:Myoflex;triethanolamine salicylate;trolamine salicylate

Chemical Property of Trolamine salicylate

Chemical Property:

• Appearance/Colour: pale yellow to amber crystalline solid
• Vapor Pressure: 8.38E-06mmHg at 25°C
• Refractive Index: n20/D 1.509
• Boiling Point: 335.4 °C at 760 mmHg
• Flash Point: 185 °C
• PSA: 121.46000
• Density: 1.209 g/mL at 25 °C
• LogP: -0.64430
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 7
• Exact Mass: 287.13688739
• Heavy Atom Count: 20
• Complexity: 189

Purity/Quality:

98%, ^*data from raw suppliers

Trolamine salicylate analytical standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38-22
• Safety Statements: 24/25-36-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(=O)O)O.C(CO)N(CCO)CCO
• Uses: TriethanolaMine salicylate can be used as intermediate in the manufacture of surface active agents, textile specialties, waxes, polishes, herbicides, petroleum demulsifiers, toilet goods, cement additives, cutting oils. In making emulsions with mineral and vegetable oils, paraffin and waxes. Solvent for casein, shellac, dyes; manufacture of synthetic resins; increasing the penetration of organic liquids into wood and paper. In the production of lubricants for the textile industry. Pharmaceutic aid (alkalizer). TEA-salicylate is a chemical uVB absorber. This is one of the 21 FDAapproved sunscreen chemicals with an approved usage level of 5 to 12 percent. TeA-salicylate is a water-soluble chemical with limited uV absorption capability. Formulators may also use it as a preservative.

Technology Process of Trolamine salicylate

There total 3 articles about Trolamine salicylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

triethanolamine (102-71-6,64114-46-1) + salicylic acid (69-72-7,25496-36-0,8052-31-1) → triethanolamine salicylate (2174-16-5)

Guidance literature:

In methanol; for 1h; Reflux;

DOI:10.1134/S1070363215120075

Reference yield: 99.0%

triethanolamine (102-71-6,64114-46-1) + aspirin (50-78-2,98201-60-6) → triethanolamine salicylate (2174-16-5)

Guidance literature:

With methanol; for 1h; Reflux;

DOI:10.1007/s11172-012-0172-9

Reference yield:

→ triethanolamine salicylate (2174-16-5)

Guidance literature:

upstream raw materials:

triethanolamine

aspirin

salicylic acid

Refernces

• 1、 Kondratenko,Kochina,Fundamensky,Ignatyev,Panikorovskii,Nyanikova. "Triethanolammonium salicylate — Protic alkanolammonium ionic liquid". . p. 1218 - 1224. Retrieved 2016.
• 2、 -. "The hydrophilic ionic liquid at room temperature and its use". Paragraph 0105; 0106. . Retrieved 2019/09/11.