3-(4-Fluorophenoxy)benzyl Bromide

Base Information

• Chemical Name: 3-(4-Fluorophenoxy)benzyl Bromide
• CAS No.: 65295-58-1
• Molecular Formula: C13H10 Br F O
• Molecular Weight: 281.12
• Hs Code.: 2909309090
• European Community (EC) Number: 670-970-3
• DSSTox Substance ID: DTXSID60372078
• Nikkaji Number: J208.525I
• Wikidata: Q72475598
• Mol file: 65295-58-1.mol

Synonyms:3-(4-Fluorophenoxy)benzyl Bromide;65295-58-1;1-(bromomethyl)-3-(4-fluorophenoxy)benzene;3'-Bromomethyl-4-fluorodiphenyl Ether;Benzene, 1-(bromomethyl)-3-(4-fluorophenoxy)-;SCHEMBL378897;DTXSID60372078;JGFSTQUUDSBQCO-UHFFFAOYSA-N;3-(p-Fluorophenoxy)benzyl bromide;3-(4-fluorophenoxy)-benzyl bromide;MFCD00059915;AKOS015853493;AB91118;AM82935;AS-81356;1-(4-Fluorophenoxy)-3-(bromomethyl)benzene;F0243;FT-0613663;T72783;A835052;1-(Bromomethyl)-3-(4-fluorophenoxy)benzene, AldrichCPR

Chemical Property of 3-(4-Fluorophenoxy)benzyl Bromide

Chemical Property:

• Boiling Point: 160 °C
• PSA: 9.23000
• Density: 1,43 g/cm3
• LogP: 4.51290
• Storage Temp.: 2-8°C
• Sensitive.: Lachrymatory
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 279.98991
• Heavy Atom Count: 16
• Complexity: 204

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-(4-Fluorophenoxy)benzyl Bromide >97.0%(GC) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T,Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)OC2=CC=C(C=C2)F)CBr

Technology Process of 3-(4-Fluorophenoxy)benzyl Bromide

There total 1 articles about 3-(4-Fluorophenoxy)benzyl Bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-(4-Fluorophenoxy)benzyl bromide (65295-58-1)

Guidance literature:

Reference yield: 81.0%

3-(4-Fluorophenoxy)benzyl bromide (65295-58-1) + (piperidin-4-yl)carbamic acid tert-butyl ester (73874-95-0) → tert-butyl (1-(3-(4-fluorophenoxy)benzyl)piperidin-4-yl)carbamate

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; Inert atmosphere;

DOI:10.1021/acs.jmedchem.7b00924

Reference yield: 74.0%

2-(3,4-dichlorophenyl)-2-methylpropan-1-ol + 3-(4-Fluorophenoxy)benzyl bromide (65295-58-1) → 3-(4-fluorophenoxy)benzyl 2-(3,4-dichlorophenyl)-2-methylpropyl ether (80843-69-2)

Guidance literature:

In N,N-dimethyl-formamide; toluene;

Downstream raw materials:

3-[3-(4-fluoro-phenoxy)-benzyl]-2-oxo-imidazolidine-1,5-dicarboxylic acid 1-benzyl ester 5-tert-butyl ester

(R)-1-[3-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazolidine-4-carboxylic acid

C₂₈H₃₀FNO₆

3,3-bis(3-(4-fluorophenoxy)benzylthio)-2-pyridylacrylonitrile

Refernces