(S)-tert-butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate

Base Information Edit

Chemical Name:(S)-tert-butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate
CAS No.:199174-24-8
Molecular Formula:C10H19NO3
Molecular Weight:201.266
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80363862
Nikkaji Number:J3.260.656C
Wikidata:Q72449613
Mol file:199174-24-8.mol

Synonyms:199174-24-8;(S)-tert-butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate;(S)-1-Boc-(3-Hydroxymethyl)pyrrolidine;tert-butyl (3S)-3-(hydroxymethyl)pyrrolidine-1-carboxylate;(S)-1-Boc-3-Hydroxymethyl-pyrrolidine;(S)-3-Hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester;MFCD03094726;1,1-DIMETHYLETHYL (3S)-3-(HYDROXYMETHYL)-1-PYRROLIDINECARBOXYLATE;(S)-1-N-Boc-3-(hydroxymethyl)pyrrolidine;3(S)-HYDROXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-BOC-(S)-(3-HYDROXYMETHYL)PYRROLIDINE;SCHEMBL515486;(R)-3-Hydroxymethylpyrrolidine-1-carboxylic acid tert-butyl ester;DTXSID80363862;tert-butyl (S)-3-(hydroxymethyl)pyrrolidine-1-carboxylate;N-Boc-3S-hydroxymethylpyrrolidine;CS-D0747;AKOS015841269;AKOS015897921;AC-1639;(S)-1-BOC-3-PYRROLIDINEMETHANOL;AS-81143;TS-02862;A4362;AM20090143;EN300-4256074;J-502218;J-504334;tert-butyl (S)-3-hydroxymethylpyrrolidine-1-carboxylate;tert-butyl(3S)-3-(hydroxymethyl)pyrrolidine-1-carboxylate;(S)-3-hydroxymethylpyrrolidine-1-carboxylic acid t-butyl ester;(S)-3-hydroxymethyl-pyrrolidine-1-carboxylic acid t-butyl ester;3beta-(Hydroxymethyl)pyrrolidine-1-carboxylic acid tert-butyl ester

Suppliers and Price of (S)-tert-butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-3-Hydroxymethyl-pyrrolidine-1-carboxylicacidtert-butylester
1g
$ 75.00

SynQuest Laboratories
(3S)-3-(Hydroxymethyl)pyrrolidine, N-Boc protected
25 g
$ 880.00

SynQuest Laboratories
(3S)-3-(Hydroxymethyl)pyrrolidine, N-Boc protected
5 g
$ 250.00

SynQuest Laboratories
(3S)-3-(Hydroxymethyl)pyrrolidine, N-Boc protected
1 g
$ 78.00

Oakwood
(S)-1-Boc-3-Hydroxymethyl-pyrrolidine 96%
250mg
$ 15.00

Oakwood
(S)-1-Boc-3-Hydroxymethyl-pyrrolidine 96%
1g
$ 25.00

Oakwood
(S)-1-Boc-3-Hydroxymethyl-pyrrolidine 96%
5g
$ 100.00

Matrix Scientific
(S)-tert-Butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate 96%
1g
$ 200.00

Matrix Scientific
(S)-tert-Butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate 96%
5g
$ 598.00

J&W Pharmlab
3(S)-Hydroxymethyl-pyrrolidine-1-carboxylicacidtert-butylester 96%
25g
$ 298.00

Total 99 raw suppliers

Chemical Property of (S)-tert-butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate Edit

Chemical Property:

Vapor Pressure:0.000241mmHg at 25°C
Refractive Index:1.483
Boiling Point:289.5 °C at 760 mmHg
PKA:14.93±0.10(Predicted)
Flash Point:128.9 °C
PSA：49.77000
Density:1.084 g/cm³
LogP:1.17360
Storage Temp.:2-8°C
Water Solubility.:Slightly soluble in water.
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:201.13649347
Heavy Atom Count:14
Complexity:210

Purity/Quality:

99% ^*data from raw suppliers

(S)-3-Hydroxymethyl-pyrrolidine-1-carboxylicacidtert-butylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(C1)CO
Isomeric SMILES:CC(C)(C)OC(=O)N1CC[C@@H](C1)CO
Uses It is used as a pharmaceutical intermediate.

Technology Process of (S)-tert-butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate

There total 14 articles about (S)-tert-butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%