1-(phenylsulfonyl)-2-propanol

Base Information

• Chemical Name: 1-(phenylsulfonyl)-2-propanol
• CAS No.: 68276-72-2
• Molecular Formula: C₉H₁₂O₃S
• Molecular Weight: 200.258
• Mol file: 68276-72-2.mol

Synonyms:1-(phenylsulfonyl)-2-propanol

Chemical Property of 1-(phenylsulfonyl)-2-propanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(phenylsulfonyl)-2-propanol

There total 20 articles about 1-(phenylsulfonyl)-2-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-phenylsulfanyl-propan-2-ol (937-56-4) → 1-(phenylsulfonyl)-2-propanol (68276-72-2)

Guidance literature:

With phenylphosphonate; dihydrogen peroxide; methyl tri-n-octyl ammonium hydrogen sulfate; sodium tungstate; at 25 ℃; for 9h;

DOI:10.1016/S0040-4020(01)00068-0

Reference yield: 95.0%

methylphenylsulfonate (3112-85-4) + acetaldehyde (75-07-0,9002-91-9) → 1-(phenylsulfonyl)-2-propanol (68276-72-2)

Guidance literature:

With n-propylmagnesium bromide; In tetrahydrofuran; 1.) room temp., 1 h; 2.) reflux;

Reference yield: 89.0%

Acetic acid 2-benzenesulfonyl-1-methyl-ethyl ester (203641-90-1) → 1-(phenylsulfonyl)-2-propanol (68276-72-2)

Guidance literature:

With potassium carbonate; for 3h; Heating;

DOI:10.1080/00304949809355272

upstream raw materials:

1-phenylsulfanyl-propan-2-ol

1-phenylsulfonyl-2-propanone

(allylsulfonyl)benzene

methylphenylsulfonate

Downstream raw materials:

(2R,3R,4R)-3-Benzenesulfonyl-pentadecane-2,4-diol

(2R,3R,4S)-3-Benzenesulfonyl-pentadecane-2,4-diol

(S)-(+)-1-(phenylsulfonyl)propan-2-ol

(R)-1-(phenylsulphonyl)propan-2-ol

Refernces

• 1、 Veisi, Hojat,Eshbala, Fereshteh Hosseini,Hemmati, Saba,Baghayeri, Mehdi. "Selective hydrogen peroxide oxidation of sulfides to sulfones with carboxylated multi-walled carbon nano tubes (MWCNTs-COOH) as heterogeneous and recyclable nanocatalysts under organic solvent-free conditions". . p. 10152 - 10158. Retrieved 2015/02/05.
• 2、 Mauleon, Pablo,Alonso, Ines,Rivero, Marta Rodriguez,Carretero, Juan C.. "Enantioselective synthesis of chiral sulfones by Rh-catalyzed asymmetric addition of boronic acids to α,β-unsaturated 2-pyridyl sulfones". . p. 9924 - 9935. Retrieved 2008/03/28.