3-Bromo-2,6-dichloropyridine

Base Information

• Chemical Name: 3-Bromo-2,6-dichloropyridine
• CAS No.: 866755-20-6
• Molecular Formula: C5H2BrCl2N
• Molecular Weight: 226.888
• Hs Code.: 2933399090
• Mol file: 866755-20-6.mol

Synonyms:3-bromo-2,6-dichloropyridine

Chemical Property of 3-Bromo-2,6-dichloropyridine

Chemical Property:

• Vapor Pressure: 0.027mmHg at 25°C
• Melting Point: 68-71 °C
• Refractive Index: 1.597
• Boiling Point: 254.972 °C at 760 mmHg
• PKA: -3.79±0.10(Predicted)
• Flash Point: 108.003 °C
• PSA: 12.89000
• Density: 1.848 g/cm³
• LogP: 3.15090

Purity/Quality:

99% ^*data from raw suppliers

3-Bromo-2,6-dichloropyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,T
• Statements: 25-37/38-41
• Safety Statements: 26-39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Bromo-2,6-dichloropyridine

There total 1 articles about 3-Bromo-2,6-dichloropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-bromo-2, 6-dichloropyridine (866755-20-6)

Guidance literature:

Reference yield: 93.0%

3-bromo-2, 6-dichloropyridine (866755-20-6) + sodium methylate (124-41-4) → 3 -bromo-6-chloro-2-methoxypyridine (1211526-62-3)

Guidance literature:

With methanol; In acetonitrile;

DOI:10.1021/acs.oprd.8b00059

Reference yield: 70.0%

3-bromo-2, 6-dichloropyridine (866755-20-6) + 4-methyl-5-nitrophenol (2042-14-0) → 3-bromo-6-chloro-2-(4-methyl-3-nitrophenoxy)pyridine

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; for 8h; regioselective reaction; Heating;

DOI:10.1021/acs.jmedchem.9b00631

Downstream raw materials:

3-bromo-2,6-difluoro-pyridine

3-bromo-2,6-diethoxypyridine

3-bromo-6-chloro-2-ethoxypyridine

Refernces