C₁₁H₁₁N₃

Base Information

• Chemical Name: C₁₁H₁₁N₃
• CAS No.: 1279722-86-9
• Molecular Formula: C₁₁H₁₁N₃
• Molecular Weight: 185.228
• Mol file: 1279722-86-9.mol

Synonyms:C₁₁H₁₁N₃

Chemical Property of C₁₁H₁₁N₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₁H₁₁N₃

There total 5 articles about C₁₁H₁₁N₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

C11H13N (1279722-82-5) → C11H11N3 (1279722-86-9)

Guidance literature:

With triflic azide; copper(II) sulfate; triethylamine; In methanol; dichloromethane; water; at 20 ℃; Inert atmosphere;

DOI:10.1002/anie.201006917

Reference yield:

4-bromobutylphosphonium bromide (7333-63-3) + 2-azidobenzaldehyde (16714-25-3) → C11H11N3 (1279722-86-9)

Guidance literature:

4-bromobutylphosphonium bromide; With sodium hydride; In tetrahydrofuran; for 12h; Reflux; Inert atmosphere; Schlenk technique;

2-azidobenzaldehyde; In tetrahydrofuran; at 50 ℃; for 4h; Reflux; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201603074

Reference yield:

C11H11NO2 → C11H11N3 (1279722-86-9)

Guidance literature:

Multi-step reaction with 2 steps

1: iron; acetic acid / ethanol / 80 °C / Inert atmosphere

2: triflic azide; copper(II) sulfate; triethylamine / methanol; dichloromethane; water / 20 °C / Inert atmosphere

With triflic azide; iron; copper(II) sulfate; acetic acid; triethylamine; In methanol; ethanol; dichloromethane; water;

DOI:10.1002/anie.201006917

upstream raw materials:

C₁₁H₁₃N

diethyl 2-nitrobenzylphosphonate

4-bromobutylphosphonium bromide

2-azidobenzaldehyde

Downstream raw materials:

2,3-dihydro-1H-cyclopentindole

Refernces

• 1、 Sun, Ke,Liu, Sheng,Bec, Patryk M.,Driver, Tom G.. "Rhodium-catalyzed synthesis of 2,3-disubstituted indoles from β,β-Disubstituted stryryl azides". . p. 1702 - 1706. Retrieved 2011/04/24.