3-phenyl-3-(2-pyridyl)propanal

Base Information

• Chemical Name: 3-phenyl-3-(2-pyridyl)propanal
• CAS No.: 100866-24-8
• Molecular Formula: C₁₄H₁₃NO
• Molecular Weight: 211.263
• Mol file: 100866-24-8.mol

Synonyms:3-phenyl-3-(2-pyridyl)propanal

Chemical Property of 3-phenyl-3-(2-pyridyl)propanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-phenyl-3-(2-pyridyl)propanal

There total 11 articles about 3-phenyl-3-(2-pyridyl)propanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(2-[1,3]dioxolan-2-yl-1-phenyl-ethyl)-pyridine (233760-11-7) → 3-phenyl-3-(2-pyridyl)propanal (100866-24-8)

Guidance literature:

With hydrogenchloride; In methanol; at 20 ℃; for 24h;

Reference yield: 80.0%

2-hydroxy-4-phenyl-4-pyridin-2-yl-butyric acid → 3-phenyl-3-(2-pyridyl)propanal (100866-24-8)

Guidance literature:

With tetrabutylammonium periodite; In 1,4-dioxane; for 20h; Heating;

Reference yield:

2-(1-phenylvinyl)pyridine (15260-65-8) + carbon monoxide (201230-82-2) → 3-phenyl-3-(2-pyridyl)propanal (100866-24-8) + 2-phenyl-2-(pyridin-2-yl)propanal

Guidance literature:

With hydrogen; carbonylhydridetris(triphenylphosphine)rhodium(I); In benzene; at 80 ℃; for 24h; under 76000 Torr; Yield given. Yields of byproduct given;

DOI:10.1021/jo00102a044

upstream raw materials:

2-(1-phenylvinyl)pyridine

carbon monoxide

2-(2-[1,3]dioxolan-2-yl-1-phenyl-ethyl)-pyridine

2-Benzylpyridine

Downstream raw materials:

pheniramine

Refernces

• 1、 Botteghi, Carlo,Chelucci, Giorgio,Ponte, Gino Del,Marchetti, Mauro,Paganelli, Stefano. "New Synthetic Route to Pheniramines via Hydroformylation of Functionalized Olefins". . p. 7125 - 7127. Retrieved 2007/10/02.