[2,6-¹³C₂]4-nitrophenol

Base Information

• Chemical Name: [2,6-¹³C₂]4-nitrophenol
• CAS No.: 70479-88-8
• Molecular Formula: C₆H₅NO₃
• Molecular Weight: 141.089
• Mol file: 70479-88-8.mol

Synonyms:[2,6-¹³C₂]4-nitrophenol

Chemical Property of [2,6-¹³C₂]4-nitrophenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2,6-¹³C₂]4-nitrophenol

There total 2 articles about [2,6-¹³C₂]4-nitrophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

[1,3-13C2]-acetone (7217-25-6) + nitromalondialdehyde sodium salt (34461-00-2) → [2,6-13C2]4-nitrophenol (70479-88-8)

Guidance literature:

With sodium hydroxide; In water; at 0 - 4 ℃; for 144h;

DOI:10.1039/c4ob01129e

Reference yield:

→ [2,6-13C2]4-nitrophenol (70479-88-8)

Guidance literature:

in 90percentiger ¹³C-Anreicherung (S. 2893);

DOI:10.1021/jo01330a014

Reference yield: 90.0%

[2,6-13C2]4-nitrophenol (70479-88-8) → [2,6-13C2]4-aminophenol (111238-55-2)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; Flow reactor;

DOI:10.1039/c4ob01129e

upstream raw materials:

[1,3-13C₂]-acetone

nitromalondialdehyde sodium salt

Downstream raw materials:

C₄⁽¹³⁾C₂H₇NO*ClH

<2,6-13C2>phenol

L-<3',5'-13C2>tyrosine

L-<3',5'-13C2>tyrosine benzyl ester p-toluenesulfonate

Refernces

• 1、 Walker, T. E.,Matheny, C.,Storm, C. B.,Hayden, H.. "An Efficient Chemomicrobiological Synthesis of Stable Isotope-Labeled L-Tyrosine and L-Phenylalanine". . p. 1175 - 1179. Retrieved 2007/10/02.