pentafluoroethyl pentafluorophenyl ketone

Base Information

• Chemical Name: pentafluoroethyl pentafluorophenyl ketone
• CAS No.: 52447-16-2
• Molecular Formula: C₉F₁₀O
• Molecular Weight: 314.082
• Mol file: 52447-16-2.mol

Synonyms:pentafluoroethyl pentafluorophenyl ketone

Chemical Property of pentafluoroethyl pentafluorophenyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of pentafluoroethyl pentafluorophenyl ketone

There total 4 articles about pentafluoroethyl pentafluorophenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

Perfluoropropylbenzene (54326-26-0) → pentafluoroethyl pentafluorophenyl ketone (52447-16-2)

Guidance literature:

With antimony pentafluoride; trifluoroacetic acid; at 50 ℃; for 7.5h;

DOI:10.1016/j.jfluchem.2007.05.020

Reference yield:

perfluoropropionic acid methyl ester (378-75-6) + bromopentafluorobenzene (344-04-7) → pentafluoroethyl pentafluorophenyl ketone (52447-16-2)

Guidance literature:

bromopentafluorobenzene; With n-butyllithium; In diethyl ether; hexane; at -80 ℃; for 1h; Inert atmosphere;

perfluoropropionic acid methyl ester; In diethyl ether; hexane; at -80 ℃; for 0.25h; Inert atmosphere;

DOI:10.1039/c4nj00136b

Reference yield:

pentafluorobenzoylchloride (2251-50-5) + [(Ph3P)Cu(1,10-phenanthroline)C2F5] → [(Ph3P)Cu(1,10-phenanthroline)Cl] (14751-81-6) + pentafluoroethyl pentafluorophenyl ketone (52447-16-2)

Guidance literature:

In tetrahydrofuran; at 23 ℃; for 0.2h; Glovebox; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201500341

upstream raw materials:

Perfluoropropylbenzene

perfluoropropionic acid methyl ester

bromopentafluorobenzene

pentafluorobenzoylchloride

Downstream raw materials:

pentafluoropropionic acid

Pentafluorobenzene

Refernces

• 1、 Mu?oz, Bianca K.,Ojo, Wilfried-Solo,Jacob, Kane,Romero, Nuria,Vendier, Laure,Despagnet-Ayoub, Emmanuelle,Etienne, Michel. "Perfluorinated 1H-indazoles and hydrotris(indazol-1-yl)borates. Supramolecular organization and a new synthetic procedure to form scorpionate ligands". . p. 2451 - 2461. Retrieved 2014/06/09.