4,5-DIFLUOROPHTHALIC ANHYDRIDE

Base Information

• Chemical Name: 4,5-DIFLUOROPHTHALIC ANHYDRIDE
• CAS No.: 18959-30-3
• Molecular Formula: C8H2F2O3
• Molecular Weight: 184.099
• Hs Code.: 29329990
• Mol file: 18959-30-3.mol

Synonyms:Phthalicanhydride, 4,5-difluoro- (8CI);5,6-difluoro-1,3-Isobenzofurandione;

Chemical Property of 4,5-DIFLUOROPHTHALIC ANHYDRIDE

Chemical Property:

• Vapor Pressure: 0.000302mmHg at 25°C
• Melting Point: 99-100℃
• Refractive Index: 1.555
• Boiling Point: 321.228 °C at 760 mmHg
• Flash Point: 143.262 °C
• PSA: 43.37000
• Density: 1.659 g/cm³
• LogP: 1.27540
• Storage Temp.: Store below +30°C.

Purity/Quality:

98%,99%, ^*data from raw suppliers

4,5-Difluorophthalic Anhydride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,5-DIFLUOROPHTHALIC ANHYDRIDE

There total 4 articles about 4,5-DIFLUOROPHTHALIC ANHYDRIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4,5-difluorophthalic acid (18959-31-4) → 4,5-difluorophthalic anhydride (18959-30-3)

Guidance literature:

With acetic anhydride; at 120 ℃; for 12h;

Reference yield: 95.0%

→ 4,5-difluorophthalic anhydride (18959-30-3)

Guidance literature:

Reference yield: 60.0%

4,5-dichlorophthalic anhydride (942-06-3) → 4,5-difluorophthalic anhydride (18959-30-3)

Guidance literature:

With potassium fluoride; In sulfolane; at 185 ℃; for 3h; Inert atmosphere;

DOI:10.1002/anie.201610944

upstream raw materials:

4,5-dichlorophthalic anhydride

4,5-dichlorophthalic acid

4,5-difluorophthalic acid

Downstream raw materials:

5,6-difluoro-1H-indene-1,3-(2H)-dione

2–(5,6–difluoro–3–oxo–2,3–dihydro–1H–inden–1–ylidene)malononitrile

Refernces

• 1、 Yao, Huifeng,Cui, Yong,Yu, Runnan,Gao, Bowei,Zhang, Hao,Hou, Jianhui. "Design, Synthesis, and Photovoltaic Characterization of a Small Molecular Acceptor with an Ultra-Narrow Band Gap". supporting information. p. 3045 - 3049. Retrieved 2017/03/13.
• 2、 Braish,Fox. "Synthesis of 2-bromo-4,5-difluorobenzoic acid". . p. 3067 - 3074. Retrieved 2007/10/02.