1,5-Dibromo-2,4-dimethoxybenzene

Base Information

• Chemical Name: 1,5-Dibromo-2,4-dimethoxybenzene
• CAS No.: 24988-36-1
• Molecular Formula: C8H8Br2O2
• Molecular Weight: 295.958
• Hs Code.: 2909309090
• DSSTox Substance ID: DTXSID80369602
• Nikkaji Number: J876.223F
• Wikidata: Q72464188
• Mol file: 24988-36-1.mol

Synonyms:1,5-dibromo-2,4-dimethoxybenzene;24988-36-1;1,3-Dibromo-4,6-dimethoxybenzene;4,6-dibromo-1,3-dimethoxybenzene;Benzene, 1,5-dibromo-2,4-dimethoxy-;MFCD00061097;1,5-Dibromo-2,4-dimethoxy benzene;2,4-dibromo-1,5-dimethoxybenzene;Maybridge3_005611;3-Methoxy-4,6-dibromoanisole;SCHEMBL1104878;1,5-dibromo2,4-dimethoxybenzen;DTXSID80369602;SVPXSTJZZSDWIA-UHFFFAOYSA-N;4,6-Dibrom-resorcin-dimethylather;HMS1446P01;AMY18061;BBL101938;STL555735;AKOS004903445;AB89981;CCG-245352;DS-4844;IDI1_016998;SY104324;1,5-bis(bromanyl)-2,4-dimethoxy-benzene;CS-0150486;FT-0658447;A817592;AE-641/00573016;1,5-dibromo-2,4-dimethoxybenzene (en)benzene, 1,5-dibromo-2,4-dimethoxy- (en)

Chemical Property of 1,5-Dibromo-2,4-dimethoxybenzene

Chemical Property:

• Vapor Pressure: 0.00166mmHg at 25°C
• Melting Point: 141.5 °C
• Refractive Index: 1.561
• Boiling Point: 303.564 °C at 760 mmHg
• Flash Point: 122.031 °C
• PSA: 18.46000
• Density: 1.743 g/cm³
• LogP: 3.22880
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 295.88706
• Heavy Atom Count: 12
• Complexity: 129

Purity/Quality:

99% ^*data from raw suppliers

1,5-Dibromo-2,4-dimethoxybenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1Br)Br)OC

Technology Process of 1,5-Dibromo-2,4-dimethoxybenzene

There total 47 articles about 1,5-Dibromo-2,4-dimethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,3-Dimethoxybenzene (151-10-0) → 4,6-dibromo-1,3-dimethoxybenzene (24988-36-1)

Guidance literature:

With oxygen; lithium bromide; copper(ll) bromide; In acetic acid; at 60 ℃; under 760.051 Torr; regioselective reaction;

DOI:10.1039/b915487f

Reference yield: 85.0%

1-Bromo-2,4-dimethoxybenzene (17715-69-4) → 4,6-dibromo-1,3-dimethoxybenzene (24988-36-1)

Guidance literature:

With DMd; sulfuric acid; sodium bromide; In acetone; at 20 ℃; for 0.0166667h;

DOI:10.1081/SCC-100105667

Reference yield: 30.0%

1,3-Dimethoxybenzene (151-10-0) → 1-Bromo-2,4-dimethoxybenzene (17715-69-4) + 4,6-dibromo-1,3-dimethoxybenzene (24988-36-1)

Guidance literature:

With bromine; In acetic acid; at 25 ℃; for 0.1h;

DOI:10.1016/j.tetlet.2004.04.112

upstream raw materials:

1-Bromo-2,4-dimethoxybenzene

4,6-dibromo-3-methoxyphenol

2,4 dimethoxybenzoic acid

5-bromo-2,4-dimethoxybenzoic acid

Downstream raw materials:

(5-bromo-2,4-dimethoxy-phenyl)-diphenyl-methanol

((CH₃O)2)benzenetriiodide

2-[5-(1-Hydroxy-1-methyl-ethyl)-2,4-dimethoxy-phenyl]-propan-2-ol

1-Bromo-2,4-dimethoxybenzene

Refernces

• 1、 -. "Nitrogen-containing compound, electronic element, and electronic device". Paragraph 0166-0167. . Retrieved 2021/01/24.
• 2、 Beil, Sebastian B.,Bomm, Alexander,Breiner, Manuel,Holtkamp, Michael,Karst, Uwe,Müller, Timo,Schüll, Aaron,Schade, Wolfgang,Schollmeyer, Dieter,Schulz, Lara,Waldvogel, Siegfried R.. "About the selectivity and reactivity of active nickel electrodes in C-C coupling reactions". . p. 14249 - 14253. Retrieved 2020/04/23.