2-(1,3-Thiazol-2-yldisulfanyl)-1,3-thiazole

Base Information

• Chemical Name: 2-(1,3-Thiazol-2-yldisulfanyl)-1,3-thiazole
• CAS No.: 20362-54-3
• Molecular Formula: C6H4 N2 S4
• Molecular Weight: 232.375
• Hs Code.: 2934100090
• NSC Number: 617651
• DSSTox Substance ID: DTXSID80326831
• Nikkaji Number: J3.197.743F
• Wikidata: Q82088044
• Pharos Ligand ID: 3QDPYK4JGMZU
• ChEMBL ID: CHEMBL4098129
• Mol file: 20362-54-3.mol

Synonyms:20362-54-3;Thiazole, 2,2'-dithiobis-;2-(1,3-thiazol-2-yldisulfanyl)-1,3-thiazole;FBPase-IN-1;2,2'-Dithiobis(thiazole);thiazolyldisulfid;NSC617651;2,2-DithiobisThiazole;2,2-Dithiobis thiazole;2,2'-Dithiobis Thiazole;SCHEMBL191350;Bis(thiazole-2-yl) persulfide;CHEMBL4098129;DTXSID80326831;2-thiazol-2-yldisulfanyl-thiazole;AKOS030240054;NSC-617651;HY-146725;CS-0438524;FT-0667731;2-(1,3- thiazol-2-yldithio)-1,3-thiazole

Chemical Property of 2-(1,3-Thiazol-2-yldisulfanyl)-1,3-thiazole

Chemical Property:

• PSA: 132.86000
• LogP: 3.39900
• Solubility.: Chloroform, Dichloromethane
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 231.92573283
• Heavy Atom Count: 12
• Complexity: 130

Purity/Quality:

98%Min ^*data from raw suppliers

2,2''-Dithiobis(thiazole) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CSC(=N1)SSC2=NC=CS2
• Uses: Shows herbicide properties.

Technology Process of 2-(1,3-Thiazol-2-yldisulfanyl)-1,3-thiazole

There total 2 articles about 2-(1,3-Thiazol-2-yldisulfanyl)-1,3-thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

Cyclohexanethiol (1569-69-3) + 2-mercaptothiazole (5685-05-2) → 2,2'-di(thiazol-2-yl)disulfide (20362-54-3) + 1,2-dicyclohexyl disulfide (2550-40-5) + C9H13NS3

Guidance literature:

With 4,6-di-tert-butyl-N-(tert-butyl)-o-aminophenol; In acetonitrile; at 20 ℃; for 4h; Electrochemical reaction;

DOI:10.1149/1945-7111/abfe43

Reference yield: 40.0%

Diphenyl-acetic acid 2-thioxo-thiazol-3-yl ester → 2,2'-di(thiazol-2-yl)disulfide (20362-54-3) + 1,1,2,2-tetraphenylethane (632-50-8) + 2-Benzhydrylsulfanyl-thiazole (114050-42-9)

Guidance literature:

In benzene; Heating;

DOI:10.1016/S0040-4020(01)86878-2

Reference yield: 50.0%

2,2'-di(thiazol-2-yl)disulfide (20362-54-3) + 4-aminotiophenol (1193-02-8) → 4-(thiazol-2-yldisulfaneyl)aniline

Guidance literature:

In chloroform; at 20 ℃; for 0.5h;

DOI:10.1016/j.ejmech.2020.112500

upstream raw materials:

Cyclohexanethiol

2-mercaptothiazole

Refernces

• 1、 Barton, Derek H. R.,Bridon, Dominique,Fernandez-Picot, Isabel,Zard, Samir Z.. "THE INVENTION OF RADICAL REACTIONS. PART XV. SOME MECHANISTIC ASPECTS OF THE DECARBOXYLATIVE REARRANGEMENT OF THIOHYDROXAMIC ESTERS". . p. 2733 - 2740. Retrieved 2007/10/02.