4-(Diethylamino)benzohydrazide

Base Information

• Chemical Name: 4-(Diethylamino)benzohydrazide
• CAS No.: 100139-54-6
• Molecular Formula: C₁₁H₁₇N₃O
• Molecular Weight: 207.275
• Hs Code.: 2928000090
• European Community (EC) Number: 674-299-7
• DSSTox Substance ID: DTXSID90366369
• Wikidata: Q27460102
• ChEMBL ID: CHEMBL1358859
• Mol file: 100139-54-6.mol

Synonyms:4-(diethylamino)benzohydrazide;100139-54-6;4-(Diethylamino)benzhydrazide;Benzoic acid, p-diethylamino-, hydrazide;4-(Diethylamino)benzenecarbohydrazide;F02;Oprea1_494949;MLS000878138;SCHEMBL961379;CHEMBL1358859;DTXSID90366369;PUNSOBLTEWFAMJ-UHFFFAOYSA-N;HMS1786N15;HMS2731K15;CS-B1392;BBL016647;MFCD01310809;STK426092;4-(diethylamino) benzenecarbohydrazide;AKOS000116105;Benzoic acid,4-(diethylamino)-,hydrazide;SMR000377068;VS-05440;FT-0676309;EN300-03686;D77291;A897582;Q27460102;Z56832298;F8889-0583;4-(Diethylamino)benzhydrazide, for HPLC derivatization, >=98.0% (HPLC)

Chemical Property of 4-(Diethylamino)benzohydrazide

Chemical Property:

• Melting Point: 99-101 °C
• Refractive Index: 1.577
• PSA: 58.36000
• Density: 1.102 g/cm³
• LogP: 2.22750
• Storage Temp.: 2-8°C
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 207.137162174
• Heavy Atom Count: 15
• Complexity: 196

Purity/Quality:

99%min ^*data from raw suppliers

4-(Diethylamino)benzohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-43-40-22
• Safety Statements: 26-36/37/39-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)C1=CC=C(C=C1)C(=O)NN

Technology Process of 4-(Diethylamino)benzohydrazide

There total 3 articles about 4-(Diethylamino)benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-N,N-diethylaniline (2052-06-4) → 4-Diaethylamino-benzoesaeure-hydrazid (100139-54-6)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) Mg, I₂, THF, (ii) /BRN= 1900390/

2: diethyl ether

3: N₂H₄*H₂O

With hydrazine hydrate; In diethyl ether;

DOI:10.1039/jr9610002365

Reference yield:

4-(diethylamino)benzoic acid (5429-28-7) → 4-Diaethylamino-benzoesaeure-hydrazid (100139-54-6)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: N₂H₄*H₂O

With hydrazine hydrate; In diethyl ether;

DOI:10.1039/jr9610002365

Reference yield:

4-diethylamino-benzoic acid methyl ester (91563-80-3) → 4-Diaethylamino-benzoesaeure-hydrazid (100139-54-6)

Guidance literature:

With hydrazine hydrate;

DOI:10.1039/jr9610002365

upstream raw materials:

4-diethylamino-benzoic acid methyl ester

4-(diethylamino)benzoic acid

4-bromo-N,N-diethylaniline