N-PROPYLCYCLOPROPANECARBOXAMIDE

Base Information

• Chemical Name: N-PROPYLCYCLOPROPANECARBOXAMIDE
• CAS No.: 26389-59-3
• Molecular Formula: C7H13NO
• Molecular Weight: 127.186
• Hs Code.: 2924299090
• Mol file: 26389-59-3.mol

Synonyms:cyclopropanecarboxamide, N-propyl-; N-PROPYLCYCLOPROPANECARBOXAMIDE

Chemical Property of N-PROPYLCYCLOPROPANECARBOXAMIDE

Chemical Property:

• Vapor Pressure: 0.00729mmHg at 25°C
• Refractive Index: 1.48
• Boiling Point: 269.3 °C at 760 mmHg
• Flash Point: 150.7 °C
• PSA: 29.10000
• Density: 1.006 g/cm³
• LogP: 1.31350
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

N-Propylcyclopropanecarboxamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-PROPYLCYCLOPROPANECARBOXAMIDE

There total 2 articles about N-PROPYLCYCLOPROPANECARBOXAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propylamine (107-10-8,42939-71-9) + cyclopropanecarboxylic acid chloride (4023-34-1) → cyclopropanecarboxylic acid 3-propyl-amide (26389-59-3)

Guidance literature:

In diethyl ether;

DOI:10.1021/jm960148m

Reference yield:

→ cyclopropanecarboxylic acid 3-propyl-amide (26389-59-3)

Guidance literature:

Cyclopropancarbonsaeurechlorid, n-Propylamin;

Reference yield:

cyclopropanecarboxylic acid 3-propyl-amide (26389-59-3) → N-(n-propyl)-N-(cyclopropanemethyl)amine (26389-60-6)

Guidance literature:

With borane-THF;

DOI:10.1021/jm960148m

upstream raw materials:

propylamine

cyclopropanecarboxylic acid chloride

Downstream raw materials:

N-(n-propyl)-N-(cyclopropanemethyl)amine

4-(cyclopropylmethyl-propyl-amino)-3,5-dinitro-benzenesulfonyl chloride

Refernces

• 1、 Whitten,Yun Feng Xie,Erickson,Webb,De Souza,Grigoriadis,McCarthy. "Rapid microscale synthesis, a new method for lead optimization using robotics and solution phase chemistry: Application to the synthesis and optimization of corticotropin-releasing factor1 receptor antagonists". . p. 4354 - 4357. Retrieved 2007/10/03.