N,N'-DIBENZYLETHYLENEDIAMINE

Base Information

• Chemical Name: N,N'-DIBENZYLETHYLENEDIAMINE
• CAS No.: 14165-27-6
• Molecular Formula: C16H20N2
• Molecular Weight: 240.348
• Hs Code.: 2921590090
• Mol file: 14165-27-6.mol

Synonyms:1,2-Ethanediamine,N,N-bis(phenylmethyl)- (9CI);Ethylenediamine, N,N-dibenzyl- (7CI,8CI);N,N-Dibenzylethylenediamine;

Chemical Property of N,N'-DIBENZYLETHYLENEDIAMINE

Chemical Property:

• Melting Point: 140-143 °C
• Refractive Index: n20/D 1.565(lit.)
• Boiling Point: 338.7 °C at 760 mmHg
• PKA: 9.58±0.10(Predicted)
• Flash Point: 147.9 °C
• PSA: 29.26000
• Density: 1.059 g/cm³
• LogP: 3.34780

Purity/Quality:

99% ^*data from raw suppliers

N1,N1-Dibenzylethane-1,2-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N'-DIBENZYLETHYLENEDIAMINE

There total 8 articles about N,N'-DIBENZYLETHYLENEDIAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-(dibenzylamino)acetamide → N,N-dibenzylethylenediamine (14165-27-6)

Guidance literature:

With borane-THF; In tetrahydrofuran; for 46h; Inert atmosphere; Reflux;

DOI:10.1002/chem.201701850

Reference yield: 63.0%

N-<2-(dibenzylamino)ethyl>phtalimide (71121-94-3) → N,N-dibenzylethylenediamine (14165-27-6)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h; Reflux;

DOI:10.1021/jm900972u

Reference yield:

N,N-dibenzylamino-acetonitrile (51643-96-0) → N,N-dibenzylethylenediamine (14165-27-6)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 1h; Ambient temperature;

DOI:10.1021/jm00142a019

upstream raw materials:

N,N-dibenzyl-2-chloroethanamine

2-(2-bromoethyl)isoindoline-1,3-dione

dibenzylamine

N,N-dibenzylamino-acetonitrile

Downstream raw materials:

4-(1H-imidazol-1-yl)-N-<2-ethyl>benzamide

N-[2-(N',N'-dibenzylamino)ethyl]-4-amino-5-chloro-2-methoxy-benzamide

N-(7-chloroquinolin-4-yl)-N'-(2-dibenzylaminoethyl)-propane-1,3-diamine

4-(1,3-dibenzyl-imidazolidin-2-yl)-phenol

Refernces

• 1、 Andrews, Simeon,Burgess, Steven J.,Skaalrud, Deborah,Kelly, Jane Xu,Peyton, David H.. "Reversal agent and linker variants of reversed chloroquines: Activities against Plasmodium falciparum". supporting information; experimental part. p. 916 - 919. Retrieved 2010/07/05.
• 2、 Iwanami,Takashima,Hirata,Hasegawa,Usuda. "Synthesis and neuroleptic activity of benzamides. cis-N-(1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy- 4-(methylamino)benzamide and related compounds". . p. 1224 - 1230. Retrieved 2007/10/02.