N,N-Dimethyl-p-phenylenediamine dihydrochloride

Base Information

• Chemical Name: N,N-Dimethyl-p-phenylenediamine dihydrochloride
• CAS No.: 536-46-9
• Molecular Formula: C8H12N2^.2(HCl)
• Molecular Weight: 209.119
• Hs Code.: 2921 51 90
• European Community (EC) Number: 208-635-7
• DSSTox Substance ID: DTXSID30883429
• Mol file: 536-46-9.mol

Synonyms:536-46-9;N,N-Dimethyl-p-phenylenediamine dihydrochloride;4-Amino-N,N-dimethylaniline dihydrochloride;N,N-Dimethyl-1,4-phenylenediamine Dihydrochloride;1,4-Benzenediamine, N,N-dimethyl-, dihydrochloride;MFCD00012991;4-N,4-N-dimethylbenzene-1,4-diamine;dihydrochloride;N,N-Dimethylbenzene-1,4-diamine dihydrochloride;N,N-dimethyl-1,4-benzenediamine dihydrochloride;N1,N1-dimethylbenzene-1,4-diamine dihydrochloride;4-dimethylaminoaniline dihydrochloride;N,N-Dimethyl-p-phenylenediammonium Dichloride;N,N-Dimethyl-p-phenylenediamine 2HCl;1,4-Amino-N,N-dimethylaniline,dihydrochloride;DMPD ⋅11b-Hydroxyandrosterone;DTXSID30883429;IAEDWDXMFDKWFU-UHFFFAOYSA-N;HY-D0209;4-Aminodimethylaniline Dihydrochloride;AKOS005256945;N,N-Dimethyl-p-phenylenediamine diHCl;CS-0010122;D0780;D3931;FT-0629500;EN300-30000;N,N-Dimethyl-p-phenylenediaminedihydrochloride;N,N-dimethyl-benzene-1,4-diamine dihydrochloride;Q-201434;N,N-Dimethyl-p-phenylenediamine dihydrochloride, 99%;F0001-1392;N,N-Dimethyl-p-phenylenediamine dihydrochloride, >=99.5% (HPLC);N,N-Dimethyl-p-phenylenediamine dihydrochloride, for microbiology, >=99.0%;N,N-Dimethyl-p-phenylenediamine dihydrochloride, suitable for peroxidase test, >=99.0% (titration)

Chemical Property of N,N-Dimethyl-p-phenylenediamine dihydrochloride

Chemical Property:

• Appearance/Colour: white to beige to grey powder
• Vapor Pressure: 0.0112mmHg at 25°C
• Melting Point: 222 °C (dec.)(lit.)
• Boiling Point: 262 °C at 760 mmHg
• Flash Point: 88.6 °C
• PSA: 29.26000
• Density: 0.94g/cm3
• LogP: 3.52000
• Storage Temp.: −20°C
• Solubility.: 2000g/l
• Water Solubility.: Soluble in water
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 208.0534038
• Heavy Atom Count: 12
• Complexity: 93.4

Purity/Quality:

98%, ^*data from raw suppliers

N,N-Dimethyl-p-phenylenediamine dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 23/24/25-43
• Safety Statements: 36/37-45

MSDS Files:

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)N.Cl.Cl
• Uses: It is a stain used in microscopy. N,N-Dimethyl-p-phenylenediamine dihydrochloride is also suitable for use in the peroxidase test. It is a compound that is normally used to measure the antioxidant potential.

Technology Process of N,N-Dimethyl-p-phenylenediamine dihydrochloride

There total 1 articles about N,N-Dimethyl-p-phenylenediamine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.3%

N,N-dimethylammonium chloride (506-59-2) + 4-chlorobenzonitrile (100-00-5) → 4-dimethylaminophenylamine dihydrochloride (536-46-9,13806-04-7)

Guidance literature:

With water; sodium hydroxide; In toluene; at 20 - 40 ℃; for 2h; Temperature; Heating;

Reference yield: 89.0%

4-dimethylaminophenylamine dihydrochloride (536-46-9,13806-04-7) + 1-(4-methoxyphenyl)ethanone (100-06-1) → (E)-4-((1-(4-methoxyphenyl)ethylidene)amino)-N,N-dimethylaniline (130597-95-4)

Guidance literature:

With potassium carbonate; In dichloromethane; water; toluene; at 160 ℃; Dean-Stark;

DOI:10.1016/j.chempr.2020.04.006

Reference yield: 88.0%

3-methoxyphenyl bromide (2398-37-0) + 4-dimethylaminophenylamine dihydrochloride (536-46-9,13806-04-7) → 4-(N,N-dimethylamino)-3’-methoxydiphenylamine (178400-99-2)

Guidance literature:

With potassium hydroxide; bis(tri-t-butylphosphine)palladium⁽⁰⁾; cetyltrimethylammonim bromide; In water; toluene; at 90 ℃; for 1h; Product distribution / selectivity;

upstream raw materials:

N,N-dimethylammonium chloride

4-chlorobenzonitrile

Downstream raw materials:

N,N-dimethyl-4-tetraphenylpyrrol-1-yl-aniline

1-(4-dimethylamino-phenyl)-1H-pyridin-4-one

N,N,N',N'-tetramethyl-para-phenylenediamine

2,5-dimethyl-[1,4]benzoquinone-mono-(4-dimethylamino-phenylimine)

Refernces