2-((E)-Hexa-3,5-dienyl)-2-((2E,4E)-5-phenyl-penta-2,4-dienyl)-malonic acid bis-(2,2,2-trifluoro-ethyl) ester

Base Information

• Chemical Name: 2-((E)-Hexa-3,5-dienyl)-2-((2E,4E)-5-phenyl-penta-2,4-dienyl)-malonic acid bis-(2,2,2-trifluoro-ethyl) ester
• CAS No.: 615547-08-5
• Molecular Formula: C₂₄H₂₄F₆O₄
• Molecular Weight: 490.443
• Mol file: 615547-08-5.mol

Synonyms:2-((E)-Hexa-3,5-dienyl)-2-((2E,4E)-5-phenyl-penta-2,4-dienyl)-malonic acid bis-(2,2,2-trifluoro-ethyl) ester

Chemical Property of 2-((E)-Hexa-3,5-dienyl)-2-((2E,4E)-5-phenyl-penta-2,4-dienyl)-malonic acid bis-(2,2,2-trifluoro-ethyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-((E)-Hexa-3,5-dienyl)-2-((2E,4E)-5-phenyl-penta-2,4-dienyl)-malonic acid bis-(2,2,2-trifluoro-ethyl) ester

There total 1 articles about 2-((E)-Hexa-3,5-dienyl)-2-((2E,4E)-5-phenyl-penta-2,4-dienyl)-malonic acid bis-(2,2,2-trifluoro-ethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-1-phenyl-1,4-pentadien-3-ol (5208-89-9,129571-71-7,129646-80-6,132696-24-3) + ((E)-2-Hexa-3,5-dienyl)-malonic acid bis-(2,2,2-trifluoro-ethyl) ester → 2-((E)-Hexa-3,5-dienyl)-2-((2E,4E)-5-phenyl-penta-2,4-dienyl)-malonic acid bis-(2,2,2-trifluoro-ethyl) ester (615547-08-5)

Guidance literature:

(E)-1-phenyl-1,4-pentadien-3-ol; ((E)-2-Hexa-3,5-dienyl)-malonic acid bis-(2,2,2-trifluoro-ethyl) ester; With sodium hydride; In tetrahydrofuran;

With Pd(OAc)2((R)-2,2'-bis(diphenylphosphino)-1,1'-binaphtyl); triethyl borane; In tetrahydrofuran;

DOI:10.1016/S1268-7731(03)00074-2

Reference yield: 98.0%

2-((E)-Hexa-3,5-dienyl)-2-((2E,4E)-5-phenyl-penta-2,4-dienyl)-malonic acid bis-(2,2,2-trifluoro-ethyl) ester (615547-08-5) → C24H23(2)HF6O4

Guidance literature:

With [Pd(MeCN)(PPh₃)3](BF₄)2; d⁽⁴⁾-methanol; triethylamine; In tetrahydrofuran; for 1.75h; Heating;

DOI:10.1021/ol035569u

Reference yield: 91.0%

methanol (67-56-1) + 2-((E)-Hexa-3,5-dienyl)-2-((2E,4E)-5-phenyl-penta-2,4-dienyl)-malonic acid bis-(2,2,2-trifluoro-ethyl) ester (615547-08-5) → (3S,4R)-4-Allyl-3-((E)-3-methoxy-3-phenyl-propenyl)-cyclohexane-1,1-dicarboxylic acid bis-(2,2,2-trifluoro-ethyl) ester + (3R,3aS,7aR)-2-Methylene-3-((E)-styryl)-octahydro-indene-5,5-dicarboxylic acid bis-(2,2,2-trifluoro-ethyl) ester

Guidance literature:

With [Pd(MeCN)(PPh₃)3](BF₄)2; triethylamine; In tetrahydrofuran; for 1.5h; Heating;

DOI:10.1021/ol035569u

upstream raw materials:

(E)-1-phenyl-1,4-pentadien-3-ol

Refernces