5-(1,2-dimethyl-2-propenyl-1-yl)-4-hydroxy-2-methoxybenzaldehyde

Base Information

• Chemical Name: 5-(1,2-dimethyl-2-propenyl-1-yl)-4-hydroxy-2-methoxybenzaldehyde
• CAS No.: 1189552-11-1
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.268
• Mol file: 1189552-11-1.mol

Synonyms:5-(1,2-dimethyl-2-propenyl-1-yl)-4-hydroxy-2-methoxybenzaldehyde

Chemical Property of 5-(1,2-dimethyl-2-propenyl-1-yl)-4-hydroxy-2-methoxybenzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(1,2-dimethyl-2-propenyl-1-yl)-4-hydroxy-2-methoxybenzaldehyde

There total 2 articles about 5-(1,2-dimethyl-2-propenyl-1-yl)-4-hydroxy-2-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C17H22O4 (1189552-09-7) → 5-(1,2-dimethyl-2-propenyl-1-yl)-4-hydroxy-2-methoxybenzaldehyde (1189552-11-1)

Guidance literature:

With sodium hydroxide; In ethanol; at 110 ℃; for 3h;

DOI:10.1248/cpb.57.607

Reference yield: 32.0%

2-methoxy-4-[(3-methylbut-2-en-1-yl)oxy]benzaldehyde (73569-44-5) → 5-(1,2-dimethyl-2-propenyl-1-yl)-4-hydroxy-2-methoxybenzaldehyde (1189552-11-1)

Guidance literature:

2-methoxy-4-[(3-methylbut-2-en-1-yl)oxy]benzaldehyde; With N,N-dimethyl-aniline; at 185 ℃; for 26h;

With hydrogenchloride; In water; at 20 ℃;

DOI:10.1055/s-0030-1258029

Reference yield: 82.0%

3,4-dihydro-2H-pyran (110-87-2) + 5-(1,2-dimethyl-2-propenyl-1-yl)-4-hydroxy-2-methoxybenzaldehyde (1189552-11-1) → C18H24O4 (1189552-13-3)

Guidance literature:

With pyridinium p-toluenesulfonate; In dichloromethane; at 30 ℃; for 72h;

DOI:10.1248/cpb.57.607

upstream raw materials:

C₁₇H₂₂O₄

2-methoxy-4-[(3-methylbut-2-en-1-yl)oxy]benzaldehyde

Downstream raw materials:

C₁₈H₂₄O₄

Refernces

• 1、 Na, Younghwa,Cha, Jeong-Heon,Yoon, Ho-Geun,Kwon, Youngjoo. "A concise synthesis of licochalcone E and its Regio-isomer, licochalcone F". experimental part. p. 607 - 609. Retrieved 2009/12/09.