2,7-Dichloroquinoxaline

Base Information

• Chemical Name: 2,7-Dichloroquinoxaline
• CAS No.: 59489-31-5
• Molecular Formula: C8H4Cl2N2
• Molecular Weight: 199.039
• Hs Code.: 2933990090
• European Community (EC) Number: 672-361-8
• DSSTox Substance ID: DTXSID30374226
• Wikidata: Q82162743
• Mol file: 59489-31-5.mol

Synonyms:2,7-Dichloroquinoxaline;59489-31-5;2,7-Dichloro-quinoxaline;QUINOXALINE, 2,7-DICHLORO-;2,7dichloro-quinoxaline;SCHEMBL629503;2 pound not7dichloro-quinoxaline;DTXSID30374226;YNASAKVGUCRNEP-UHFFFAOYSA-N;RKL10145;MFCD03426386;2,7-dichloro-quinoxaline, AldrichCPR;AKOS006344708;AB14861;AC-6649;AS-37376;BP-10852;A8364;AM20070371;CS-0171504;FT-0647207

Chemical Property of 2,7-Dichloroquinoxaline

Chemical Property:

• Vapor Pressure: 0.0036mmHg at 25°C
• Melting Point: 141 °C
• Refractive Index: 1.67
• Boiling Point: 290.5 °C at 760 mmHg
• PKA: -2.44±0.30(Predicted)
• Flash Point: 157.1 °C
• PSA: 25.78000
• Density: 1.486 g/cm³
• LogP: 2.93660
• Storage Temp.: 2-8°C
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 197.9751535
• Heavy Atom Count: 12
• Complexity: 165

Purity/Quality:

98%min ^*data from raw suppliers

2,7-Dichloroquinoxaline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=NC=C(N=C2C=C1Cl)Cl

Technology Process of 2,7-Dichloroquinoxaline

There total 6 articles about 2,7-Dichloroquinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6- and 7-chloro-2-hydroxyquinoxaline + 4-Chloro-1,2-phenylenediamine (95-83-0) + Chloroacetamide (79-07-2) → 2,7-dichloroquinoxaline (59489-31-5)

Guidance literature:

With dihydrogen peroxide; trichlorophosphate; In sodium hydroxide; water;

Reference yield:

7-chloroquinoxaline-2(1H)-one (59489-30-4) → 2,7-dichloroquinoxaline (59489-31-5)

Guidance literature:

With trichlorophosphate;

Reference yield:

6-chloro-3,4-dihydroquinoxalin-2(1H)-one (66367-05-3) → 2,7-dichloroquinoxaline (59489-31-5)

Guidance literature:

Multi-step reaction with 2 steps

1: AgNO₃; aqueous NH₃

2: POCl₃

With ammonium hydroxide; silver nitrate; trichlorophosphate;

upstream raw materials:

7-chloroquinoxaline-2(1H)-one

6-chloro-3,4-dihydroquinoxalin-2(1H)-one

N-4-chloro-2-nitrophenylglycine

4-Chloro-2-nitroaniline

Downstream raw materials:

4-[(7-chloro-2-quinoxalinyl)thio]phenol

2-[4-(7-chloro-quinoxalin-2-yloxy)-phenylamino]-propionic acid ethyl ester

4-[(N-7-chloro-2-quinoxalinyl)amino]phenol

2-[4-(7-chloro-quinoxalin-2-yloxy)-phenoxy]-propionitrile

Refernces