3-Methoxypropanehydrazide

Base Information

• Chemical Name: 3-Methoxypropanehydrazide
• CAS No.: 21920-89-8
• Molecular Formula: C4H10N2O2
• Molecular Weight: 118.13
• Hs Code.: 2928000090
• European Community (EC) Number: 673-595-3
• DSSTox Substance ID: DTXSID90374888
• Wikidata: Q82163464
• Mol file: 21920-89-8.mol

Synonyms:3-methoxypropanehydrazide;21920-89-8;3-Methoxypropionic acid hydrazide;3-methoxypropanohydrazide;3-METHOXYPROPIONICACIDHYDRAZIDE;3-METHOXYPROPIONICACID;SCHEMBL362236;DTXSID90374888;HTNUUDFQRYBJPH-UHFFFAOYSA-N;STR07579;MFCD03789158;AKOS005292536;CS-0318297;FT-0616014;3-methoxypropionic acid hydrazide, AldrichCPR;EN300-206283;A815754;A1-09270

Chemical Property of 3-Methoxypropanehydrazide

Chemical Property:

• Vapor Pressure: 0.00302mmHg at 25°C
• Refractive Index: 1.446
• Boiling Point: 284.2 °C at 760 mmHg
• Flash Point: 125.7 °C
• PSA: 64.35000
• Density: 1.068 g/cm³
• LogP: 0.10400
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 118.074227566
• Heavy Atom Count: 8
• Complexity: 74.4

Purity/Quality:

98%Min ^*data from raw suppliers

3-Methoxypropanehydrazide 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCCC(=O)NN

Technology Process of 3-Methoxypropanehydrazide

There total 1 articles about 3-Methoxypropanehydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 3-methoxypropionate (3852-09-3) → 3-methoxypropionic acid hydrazide (21920-89-8)

Guidance literature:

With hydrazine hydrate; In ethanol; at 80 ℃;

Reference yield: 97.0%

3-methoxypropionic acid hydrazide (21920-89-8) + 5-formyl-2-nitrophenol (704-13-2) → (E)-N'-(3-hydroxy-4-nitrobenzylidene)-3-methoxypropanehydrazide

Guidance literature:

In methanol;

Reference yield: 30.0%

3-methoxypropionic acid hydrazide (21920-89-8) + tert-butyl (1-(4-(7-phenyl-2-thioxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate (1313440-37-7) → tert-butyl (1-(4-(1-(2-methoxyethyl)-8-phenyl-4H-pyrido[2,3-b][1,2,4]triazolo[4,3-d][1,4]oxazin-7-yl)phenyl)cyclobutyl)carbamate (1313441-43-8)

Guidance literature:

In xylene; at 150 ℃; for 0.25h; Microwave irradiation;

upstream raw materials:

methyl 3-methoxypropionate

Downstream raw materials:

tert-butyl (1-(4-(1-(2-methoxyethyl)-8-phenyl-4H-pyrido[2,3-b][1,2,4]triazolo[4,3-d][1,4]oxazin-7-yl)phenyl)cyclobutyl)carbamate

Refernces

• 1、 -. "HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS". Page/Page column 149. . Retrieved 2014/01/18.