7-PHENYLHEPTANOIC ACID

Base Information

• Chemical Name: 7-PHENYLHEPTANOIC ACID
• CAS No.: 40228-90-8
• Molecular Formula: C13H18O2
• Molecular Weight: 206.285
• Hs Code.: 2916399090
• Mol file: 40228-90-8.mol

Synonyms:Heptanoicacid, 7-phenyl- (6CI,7CI);7-Phenylheptanoic acid;

Chemical Property of 7-PHENYLHEPTANOIC ACID

Chemical Property:

• Vapor Pressure: 1.06E-05mmHg at 25°C
• Melting Point: 20 °C
• Refractive Index: 1.5070
• Boiling Point: 356.5 °C at 760 mmHg
• PKA: 4.77±0.10(Predicted)
• Flash Point: 253.5 °C
• PSA: 37.30000
• Density: 1.034 g/cm³
• LogP: 3.26420
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: Insoluble in water.

Purity/Quality:

99% ^*data from raw suppliers

7-Phenylheptanoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/38-36
• Safety Statements: 26-36

MSDS Files:

Useful:

• Uses: 7-Phenylheptanoic acid is used in the process to make amino acid derivatives.

Technology Process of 7-PHENYLHEPTANOIC ACID

There total 30 articles about 7-PHENYLHEPTANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(E)-7-phenylhept-4-enoic acid (344359-68-8) → 7-phenylheptanoic acid (40228-90-8)

Guidance literature:

With hydrogen; 5%-palladium/activated carbon; under 2068.65 Torr;

Reference yield: 99.0%

6-benzoylhexanoic acid (7472-43-7) → 7-phenylheptanoic acid (40228-90-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 65 ℃; for 24h; atmospheric pressure;

DOI:10.1021/jo070646a

Reference yield: 97.0%

7-phenylheptanoic acid methyl ester (101689-18-3) → 7-phenylheptanoic acid (40228-90-8)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃;

DOI:10.1021/ac051141s

upstream raw materials:

7-phenylheptanenitrile

2-benzylcyclohexane-1,3-dione

6-benzoylhexanoic acid

4-oxo-7-phenylheptanoic acid

Downstream raw materials:

7-phenylheptanoyl chloride

7-phenylheptanoic acid methyl ester

(R)-ethyl 4-(7-phenylheptanamido)octanoate

(R)-methyl 4-(7-phenylheptanamido)octanoate

Refernces

• 1、 -. "Synthetic method of terminal carboxylic acid". Paragraph 0055-0058. . Retrieved 2019/11/21.
• 2、 Pippel, Daniel J.,Mapes, Christopher M.,Mani, Neelakandha S.. "Reactions between weinreb amides and 2-magnesiated oxazoles: A simple and efficient preparation of 2-acyl oxazoles". . p. 5828 - 5831. Retrieved 2008/02/09.