2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE

Base Information

• Chemical Name: 2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE
• CAS No.: 22134-11-8
• Molecular Formula: C7H2Br3NS
• Molecular Weight: 371.878
• Hs Code.: 2930909090
• Mol file: 22134-11-8.mol

Synonyms:2,4,6-Tribromophenyl isothiocyanate;

Chemical Property of 2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE

Chemical Property:

• Vapor Pressure: 1.22E-05mmHg at 25°C
• Melting Point: 106 °C
• Refractive Index: 1.706
• Boiling Point: 380.1 °C at 760 mmHg
• Flash Point: 183.7 °C
• PSA: 44.45000
• Density: 2.21 g/cm³
• LogP: 4.70840

Purity/Quality:

98%min ^*data from raw suppliers

2,4,6-Tribromophenylisothiocyanate 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system
• Hazard Codes: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system
• Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,4,6-Tribromophenyl Isothiocyanate is used in preparation of the thiazole derivative compound and their pharmaceutical application.

Technology Process of 2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE

There total 2 articles about 2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,4,6-tribromoaniline (147-82-0) → (2,4,6-tribromophenyl)isothiocyanate (22134-11-8)

Guidance literature:

With dmap; thiophosgene; In dichloromethane; at 20 ℃; for 6h;

Reference yield:

→ (2,4,6-tribromophenyl)isothiocyanate (22134-11-8)

Guidance literature:

2.4.6-Tribromophenylamin, CSCl2;

Reference yield: 24.0%

(2,4,6-tribromophenyl)isothiocyanate (22134-11-8) + monoethanolammonium hydrogensulfate (20261-59-0,56633-27-3,85338-41-6) → Thiazolidin-(2E)-ylidene-(2,4,6-tribromo-phenyl)-amine

Guidance literature:

With sodium hydroxide; In ethanol; for 3h; Heating;

upstream raw materials:

2,4,6-tribromoaniline

Refernces