Ethenamine, N,N-dimethyl-2-nitro-

Base Information

• Chemical Name: Ethenamine, N,N-dimethyl-2-nitro-
• CAS No.: 1190-92-7
• Molecular Formula: C₄H₈N₂O₂
• Molecular Weight: 116.12
• Hs Code.: 29211990
• DSSTox Substance ID: DTXSID101305769
• Mol file: 1190-92-7.mol

Synonyms:Ethenamine, N,N-dimethyl-2-nitro-;MFCD00051519;dimethylamino-2-nitroethylene;N,N-dimethyl-2-nitroetheneamine;DTXSID101305769;AKOS025243414;AB02125;SY007004;FT-0607702

Chemical Property of Ethenamine, N,N-dimethyl-2-nitro-

Chemical Property:

• Vapor Pressure: 2.31mmHg at 25°C
• Melting Point: 103-107 °C(lit.)
• Refractive Index: 1.473
• Boiling Point: 161.115 °C at 760 mmHg
• PKA: 2.71±0.70(Predicted)
• Flash Point: 51.241 °C
• PSA: 49.06000
• Density: 1.073 g/cm³
• LogP: 0.81910
• Storage Temp.: Keep Cold
• XLogP3: -0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 116.058577502
• Heavy Atom Count: 8
• Complexity: 103

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Dimethylamino-2-nitroethylene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 22-37/38-41-43
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C=C[N+](=O)[O-]
• Uses: 1-Dimethylamino-2-nitroethylene is widely used in organic reactions. 1-(Dimethylamino)-2-nitroethylene undergoes addition-elimination reaction with indoles to form the corresponding 3-(2-nitrovinyl)indoles.

Technology Process of Ethenamine, N,N-dimethyl-2-nitro-

There total 12 articles about Ethenamine, N,N-dimethyl-2-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

nitromethane (75-52-5) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → 1-dimethylamino-2-nitroethene (73430-27-0,87446-70-6,1190-92-7)

Guidance literature:

In methanol; at 80 ℃; for 1h; Solvent; Temperature;

Reference yield: 74.0%

((E)-2-Nitro-vinylsulfanyl)-benzene (120539-85-7) + dimethyl amine (124-40-3) → 1-dimethylamino-2-nitroethene (73430-27-0,87446-70-6,1190-92-7)

Guidance literature:

In methanol; for 1h; Ambient temperature;

DOI:10.1055/s-1988-27757

Reference yield: 58.0%

nitromethane (75-52-5) + 2-aza-1,3-bis(dimethylamino)-3-methoxy-1-propen → 1-dimethylamino-2-nitroethene (73430-27-0,87446-70-6,1190-92-7)

Guidance literature:

With Trimethyl borate; In ethyl acetate;

upstream raw materials:

nitromethane

(bis-ethylsulfanyl-methyl)-dimethyl-amine

N₁,N₁-dimethyl-N₂-phenylformamidine

N,N-dimethylformamide dimethyl sulfate adduct

Downstream raw materials:

dimedone potassium salt

5-bromotryptamine

5-chlorotryptamine

2-(6-methoxy-1H-indol-3-yl)ethanamine

Refernces

• 1、 -. "Method for synthesizing 2-amino-5-nitrothiazole". Paragraph 0037; 0040; 0043-0050. . Retrieved 2020/08/06.
• 2、 -. "HETERO-HALO INHIBITORS OF HISTONE DEACETYLASE". Paragraph 262. . Retrieved 2017/01/26.