VALIDOXYLAMINE A

Base Information

• Chemical Name: VALIDOXYLAMINE A
• CAS No.: 82309-75-9
• Molecular Formula: C₁₄H₂₅NO₈
• Molecular Weight: 335.354
• Mol file: 82309-75-9.mol

Synonyms:DL-chiro-Inositol,1,5,6-trideoxy-5-(hydroxymethyl)-1-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-,stereoisomer; DL-Validoxylamine A

Chemical Property of VALIDOXYLAMINE A

Chemical Property:

• Boiling Point: 602.6±55.0 °C(Predicted)
• PKA: 13.49±0.70(Predicted)
• PSA: 173.87000
• Density: 1.61±0.1 g/cm3(Predicted)
• LogP: -4.18600

Purity/Quality:

99% ^*data from raw suppliers

VALIDOXYLAMINE A 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of VALIDOXYLAMINE A

There total 11 articles about VALIDOXYLAMINE A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-<(1SR)-(1,4,6/5)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexenyl>-(1RS)-(1,2,4/3,5,6)-2,3,4,6-tetrahydroxy-5-(hydroxymethyl)cyclohexylamine nonaacetate (81692-23-1,81739-21-1,114819-00-0) → DL-validoxylamine A (38665-10-0,79549-82-9,79549-83-0,82309-75-9,82309-79-3,82309-82-8,84622-04-8,84622-05-9)

Guidance literature:

With hydrogenchloride; for 0.833333h; Heating;

DOI:10.1021/jo00188a016

Reference yield: 100.0%

N-<(1SR)-(1,4,6/5)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexenyl>-(1SR)-(1,2,4/3,5,6)-2,3,4,6-tetrahydroxy-5-(hydroxymethyl)cyclohexylamine nonaacetate (81692-23-1,81739-21-1,114819-00-0) → DL-validoxylamine A (38665-10-0,79549-82-9,79549-83-0,82309-75-9,82309-79-3,82309-82-8,84622-04-8,84622-05-9)

Guidance literature:

With hydrogenchloride; for 0.833333h; Heating;

DOI:10.1021/jo00188a016

Reference yield:

Validoxamine A Octaacetate (79527-24-5,79549-81-8,82309-78-2,82309-81-7,84622-06-0,84622-07-1,91464-89-0) → DL-validoxylamine A (38665-10-0,79549-82-9,79549-83-0,82309-75-9,82309-79-3,82309-82-8,84622-04-8,84622-05-9)

Guidance literature:

With hydrogenchloride; at 90 ℃; for 4h;

DOI:10.1246/cl.1982.749

upstream raw materials:

Validoxamine A Octaacetate

N-<(1SR)-(1,4,6/5)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexenyl>-(1RS)-(1,2,4/3,5,6)-2,3,4,6-tetrahydroxy-5-(hydroxymethyl)cyclohexylamine nonaacetate

N-<(1SR)-(1,4,6/5)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexenyl>-(1SR)-(1,2,4/3,5,6)-2,3,4,6-tetrahydroxy-5-(hydroxymethyl)cyclohexylamine nonaacetate

Acetic acid (1R,2S,5S,6R)-5,6-diacetoxy-4-acetoxymethyl-2-((3aR,4R,5aS,9aS,9bR)-2,2,8,8-tetramethyl-hexahydro-[1,3]dioxolo[4',5':3,4]benzo[1,2-d][1,3]dioxin-4-ylamino)-cyclohex-3-enyl ester

Refernces

• 1、 Ogawa, Seiichiro,Ogawa, Takao,Chida, Noritaka,Toyokuni, Tatsushi,Suami, Tetsuo. "SYNTHESIS OF DL-VALIDOXYLAMINE A". . p. 749 - 752. Retrieved 2007/10/02.