Fmoc-DL-Arg(Pbf)-OPfp

Base Information

• Chemical Name: Fmoc-DL-Arg(Pbf)-OPfp
• CAS No.: 200132-16-7
• Molecular Formula: C₄₀H₃₉F₅N₄O₇S
• Molecular Weight: 814.83
• Hs Code.: 2935 90 90
• European Community (EC) Number: 685-319-9
• Mol file: 200132-16-7.mol

Synonyms:200132-16-7;FT-0643866;A814166;Fmoc-D-Arg(Pbf)-OPfp;ZINC150339136;200132-33-8;(2,3,4,5,6-pentafluorophenyl) 5-[[amino-[(2,2,4,6,7-pentamethyl-3H-benzofuran-5-yl)sulfonylamino]methylene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoate

Chemical Property of Fmoc-DL-Arg(Pbf)-OPfp

Chemical Property:

• Refractive Index: 1.616
• PSA: 164.29000
• Density: 1.44 g/cm3
• LogP: 9.46980
• Storage Temp.: Store at 0°C
• XLogP3: 7.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 14
• Exact Mass: 814.24596158
• Heavy Atom Count: 57
• Complexity: 1530

Purity/Quality:

98%,99%, ^*data from raw suppliers

Fmoc-Arg(Pbf)-OPfp Novabiochem? ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=C(C2=C1OC(C2)(C)C)C)S(=O)(=O)NC(=NCCCC(C(=O)OC3=C(C(=C(C(=C3F)F)F)F)F)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46)N)C

Technology Process of Fmoc-DL-Arg(Pbf)-OPfp

There total 1 articles about Fmoc-DL-Arg(Pbf)-OPfp which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Fmoc-Arg(Pbf) pentafluorophenyl ester (200132-16-7,200132-33-8)

Guidance literature:

Reference yield:

N-Fmoc L-Phe (35661-40-6) + Fmoc-Ser(tBu)-OH (71989-33-8) + Fmoc-Tyr(tBu)-OH (71989-38-3,118488-18-9,204384-67-8) + L-Asn(Trt) (132388-59-1) + trifluoroacetic acid (76-05-1) + 3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester (143824-78-6,163619-04-3) + Fmoc-Arg(Pbf) pentafluorophenyl ester (200132-16-7,200132-33-8) → kisspeptin-10

Guidance literature:

N-Fmoc L-Phe; With piperidine; 4-(2,4-dimethoxyphenyl-Fmoc-aminomethyl)phenoxy resin; benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; Rink amide resin

Fmoc-Arg(Pbf) pentafluorophenyl ester; With benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

Fmoc-Ser(tBu)-OH; Fmoc-Tyr(tBu)-OH; L-Asn(Trt); trifluoroacetic acid; 3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester; Further stages;

DOI:10.3390/molecules23123071

Refernces