3-AMINO-2-BROMO-6-METHOXYPYRIDINE

Base Information

• Chemical Name: 3-AMINO-2-BROMO-6-METHOXYPYRIDINE
• CAS No.: 135795-46-9
• Molecular Formula: C6H7BrN2O
• Molecular Weight: 203.038
• Hs Code.: 29333990
• Mol file: 135795-46-9.mol

Synonyms:2-bromo-6-methoxypyridin-3-amine

Chemical Property of 3-AMINO-2-BROMO-6-METHOXYPYRIDINE

Chemical Property:

• Vapor Pressure: 0.00167mmHg at 25°C
• Refractive Index: 1.602
• Boiling Point: 293.927 °C at 760 mmHg
• PKA: 1.12±0.10(Predicted)
• Flash Point: 131.562 °C
• PSA: 48.14000
• Density: 1.623 g/cm³
• LogP: 2.01610
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Amino-2-bromo-6-methoxypyridine ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

Useful:

Technology Process of 3-AMINO-2-BROMO-6-METHOXYPYRIDINE

There total 3 articles about 3-AMINO-2-BROMO-6-METHOXYPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6-methoxy-pyridin-3-ylamine (6628-77-9) → 2-bromo-6-methoxy-pyridin-3-ylamine (135795-46-9)

Guidance literature:

With bromine; sodium acetate; In acetic acid; at 20 ℃; for 0.5h;

Reference yield: 92.0%

2-bromo-6-methoxy-3-nitropyridine (344296-05-5) → 2-bromo-6-methoxy-pyridin-3-ylamine (135795-46-9)

Guidance literature:

With iron; ammonium chloride; In ethanol; water; at 60 ℃; for 5h; Inert atmosphere;

Reference yield:

6-methoxy-pyridin-3-ylamine (6628-77-9) → 2-bromo-6-methoxy-pyridin-3-ylamine (135795-46-9)

Guidance literature:

With benzyltrimethylazanium tribroman-2-uide; In methanol; dichloromethane; at 20 ℃; for 24h;

upstream raw materials:

6-methoxy-pyridin-3-ylamine

2-bromo-6-methoxy-3-nitropyridine

Downstream raw materials:

6-methoxy-1,5-naphthyridin-2(1H)-one

1,5-dihydro-1,5-naphthyridine-2,6-dione

[4-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,5,6,10-tetraaza-dibenzo[a,d]cyclohepten-7-yl)-phenyl]-carbamic acid tert-butyl ester

7-(6-Benzylamino-pyridin-3-yl)-5-ethyl-10-methyl-5,10-dihydro-4,5,6,10-tetraaza-dibenzo[a,d]cyclohepten-11-one

Refernces

• 1、 -. "ORGANIC SEMICONDUCTOR". Page/Page column. . Retrieved 2015/06/03.
• 2、 -. "Pyrrolopyridine Compounds, Method of Making Them and Uses Thereof". Page/Page column 9. . Retrieved 2008/12/08.