N-phenylisomaleimide

Base Information

• Chemical Name: N-phenylisomaleimide
• CAS No.: 51229-33-5
• Molecular Formula: C₁₀H₇NO₂
• Molecular Weight: 173.171
• Mol file: 51229-33-5.mol

Synonyms:N-phenylisomaleimide

Chemical Property of N-phenylisomaleimide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-phenylisomaleimide

There total 2 articles about N-phenylisomaleimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

N-phenylmaleamic acid (555-59-9,4437-08-5,37902-58-2) → N-phenylisomaleimide (51229-33-5)

Guidance literature:

With chloroformic acid ethyl ester; triethylamine; In dichloromethane; at 0 ℃;

DOI:10.1002/hlca.19830660132

Reference yield:

→ N-phenylisomaleimide (51229-33-5)

Guidance literature:

entspr. Maleamic acid, AcCl/Et3N/CH2Cl2;

DOI:10.1021/jo00805a020

Reference yield: 77.0%

N-phenylisomaleimide (51229-33-5) + Hexanoyl chloride (142-61-0) → (3R,4R)-3-Butyl-1-phenyl-5-oxa-1-aza-spiro[3.4]oct-7-ene-2,6-dione

Guidance literature:

With triethylamine; In diethyl ether; Ambient temperature;

DOI:10.1002/hlca.19830660132

upstream raw materials:

N-phenylmaleamic acid

Refernces

• 1、 Capraro,Winkler,Martin. "[2+2]-cycloaddition of 'maleic isoimides' with ketenes and reactions of spiro-β-lactams to muconic and tetramic acids". . p. 362 - 378. Retrieved 2007/10/02.