2,4,6-Trichlorobenzenesulfonamide

Base Information

• Chemical Name: 2,4,6-Trichlorobenzenesulfonamide
• CAS No.: 28460-30-2
• Molecular Formula: C6H4Cl3NO2S
• Molecular Weight: 260.52546
• Hs Code.: 2935909099
• DSSTox Substance ID: DTXSID90361495
• Wikidata: Q82143835
• Mol file: 28460-30-2.mol

Synonyms:2,4,6-Trichlorobenzenesulfonamide;28460-30-2;2,4,6-trichlorobenzenesulphonamide;2,4,6-trichlorobenzene-1-sulfonamide;Benzenesulfonamide,2,4,6-trichloro-;SCHEMBL1645227;DTXSID90361495;BBL100613;MFCD00955746;STL554407;AKOS005254871;Benzenesulfonamide, 2,4,6-trichloro-;PS-3260;2,4,6-tris(chloranyl)benzenesulfonamide;246-TRICHLORBENZENESULFONAMIDE97;2,4,6-Trichlorobenzenesulfonamide, 97%;CS-0157712;FT-0678102;E76802;EN300-271025;A819459;J-017091

Chemical Property of 2,4,6-Trichlorobenzenesulfonamide

Chemical Property:

• Vapor Pressure: 8.34E-07mmHg at 25°C
• Melting Point: 177-181 °C(lit.)
• Refractive Index: 1.612
• Boiling Point: 406.1 °C at 760 mmHg
• PKA: 9.04±0.60(Predicted)
• Flash Point: 199.4 °C
• PSA: 68.54000
• Density: 1.689 g/cm³
• LogP: 4.07530
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 258.902833
• Heavy Atom Count: 13
• Complexity: 264

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,4,6-Trichlorobenzenesulphonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1Cl)S(=O)(=O)N)Cl)Cl

Technology Process of 2,4,6-Trichlorobenzenesulfonamide

There total 4 articles about 2,4,6-Trichlorobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,6-trichlorobenzenesulfonyl chloride (51527-73-2) → 2,4,6-trichlorobenzenesulfonamide (28460-30-2)

Guidance literature:

With ammonia; water;

DOI:10.1039/jr9600003063 DOI:10.1021/ja01860a014

Reference yield:

1,3,5-trichlorobenzene (108-70-3,63697-19-8) → 2,4,6-trichlorobenzenesulfonamide (28460-30-2)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorosulfuric acid

2: water; ammonia

With chlorosulphuric acid; ammonia; water;

DOI:10.1021/ja01860a014

Reference yield:

1,3,5-trichlorobenzene (108-70-3,63697-19-8) → 2,4,6-trichlorobenzenesulfonamide (28460-30-2)

Guidance literature:

Multi-step reaction with 2 steps

1: ClSO₃H

2: NH₃ / benzene

With chlorosulfonic acid; ammonia; In benzene;

DOI:10.1039/jr9600003063

upstream raw materials:

2,4,6-trichlorobenzenesulfonyl chloride

1,3,5-trichlorobenzene

Downstream raw materials:

N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,4,6-trichloro-benzenesulfonamide

2,4,6-trichloro-N-[4-[3-[(2,4,6-trichlorophenyl)sulfonylamino]-1H-pyrazolo[3,4-b]pyrazin-6-yl]phenyl]benzenesulfonamide