OROTIC ACID LITHIUM SALT MONOHYDRATE

Base Information

• Chemical Name: OROTIC ACID LITHIUM SALT MONOHYDRATE
• CAS No.: 5266-20-6
• Molecular Formula: C5H3LiN2O4
• Molecular Weight: 162.031
• Hs Code.: 2933599090
• Mol file: 5266-20-6.mol

Synonyms:4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-, monolithium salt (9CI);Orotic acid,monolithium salt (8CI);4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-, lithium salt (1:1);

Chemical Property of OROTIC ACID LITHIUM SALT MONOHYDRATE

Chemical Property:

• Melting Point: 300oC
• PSA: 115.60000
• LogP: -1.81300

Purity/Quality:

99%, ^*data from raw suppliers

OROTIC ACID LITHIUM SALT MONOHYDRATE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of OROTIC ACID LITHIUM SALT MONOHYDRATE

There total 1 articles about OROTIC ACID LITHIUM SALT MONOHYDRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

orotic acid (65-86-1,58915-47-2,6784-70-9) → lithium orotate (5266-20-6)

Guidance literature:

With lithium hydroxide; In water; at 70 - 90 ℃; for 0.5h;

DOI:10.1039/c6ce02101h

Reference yield: 100.0%

lithium orotate (5266-20-6) → 2,4-dihydroxypyrimidine-6-carboxylic acid (65-86-1)

Guidance literature:

With hydrogenchloride; In N,N-dimethyl-formamide; at 70 ℃; for 2h;

Reference yield:

lithium orotate (5266-20-6) → 2,4-dichloropyrimidine-6-carboxylic acid chloride (26830-94-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / N,N-dimethyl-formamide / 2 h / 70 °C

2: phosphorus pentachloride; trichlorophosphate / 3 h / 20 °C / Reflux

With hydrogenchloride; phosphorus pentachloride; trichlorophosphate; In N,N-dimethyl-formamide;

upstream raw materials:

orotic acid

Downstream raw materials:

2,4-dihydroxypyrimidine-6-carboxylic acid

2,4-dichloropyrimidine-6-carboxylic acid chloride

Refernces