ethyl 3--3-oxopropionate

Base Information

• Chemical Name: ethyl 3--3-oxopropionate
• CAS No.: 152912-81-7
• Molecular Formula: C₁₇H₁₈N₂O₅S
• Molecular Weight: 362.406
• Mol file: 152912-81-7.mol

Synonyms:ethyl 3--3-oxopropionate

Chemical Property of ethyl 3--3-oxopropionate

Chemical Property:

Purity/Quality:

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Technology Process of ethyl 3--3-oxopropionate

There total 2 articles about ethyl 3--3-oxopropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

ethyl 3--3-oxopropionate → ethyl 3--3-oxopropionate (152912-81-7)

Guidance literature:

With triethylsilane; trifluoroacetic acid; at 50 ℃; for 16h;

DOI:10.1002/jhet.5570300333

Reference yield:

5-acetyl-2-phenylamino-3-nitrothiophene (1087-13-4) → ethyl 3--3-oxopropionate (152912-81-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / benzene / 30 h / Heating

2: 86 percent / trifluoroacetic acid, triethylsilane / 16 h / 50 °C

With triethylsilane; trifluoroacetic acid; In benzene;

DOI:10.1002/jhet.5570300333

Reference yield: 58.0%

ethyl 3--3-oxopropionate (152912-81-7) → 2-ethyl-4,8-dihydro-4-phenyl-5H-thieno<2,3-b><1,4>diazepin-5,7(6H)-dione

Guidance literature:

With iron; acetic acid; at 70 ℃; for 24h;

DOI:10.1002/jhet.5570300333

upstream raw materials:

5-acetyl-2-phenylamino-3-nitrothiophene

Refernces