3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE

Base Information

• Chemical Name: 3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE
• CAS No.: 782-87-6
• Molecular Formula: C13H15N3
• Molecular Weight: 213.282
• Mol file: 782-87-6.mol

Synonyms:Propionitrile,3,3'-(benzylimino)di- (6CI,7CI,8CI);

Chemical Property of 3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE

Chemical Property:

• Boiling Point: 429.3 °C at 760 mmHg
• Flash Point: 195.3 °C
• PSA: 50.82000
• Density: 1.072 g/cm³
• LogP: 2.31596

Purity/Quality:

99% ^*data from raw suppliers

3-[Benzyl-(2-cyano-ethyl)-amino]-propionitrile 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE

There total 8 articles about 3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

acrylonitrile (107-13-1,25014-41-9) + benzylamine (100-46-9) → N-benzylbis(2-cyanoethyl)amine (782-87-6)

Guidance literature:

With hydroquinone; at 140 ℃; for 168h;

DOI:10.1021/jo00335a041

Reference yield: 94.0%

acrylonitrile (107-13-1,25014-41-9) + benzylamine (100-46-9) → 3-(benzylamino)propionitrile (706-03-6) + N-benzylbis(2-cyanoethyl)amine (782-87-6)

Guidance literature:

1-butyl-3-methylimidazolium Tetrafluoroborate; In water; at 20 ℃; for 7h;

DOI:10.1039/b312047c

Reference yield: 89.0%

3,3'-Iminodipropionitrile (111-94-4) + benzyl chloride (100-44-7) → N-benzylbis(2-cyanoethyl)amine (782-87-6)

Guidance literature:

With sodium carbonate; sodium iodide; In acetonitrile; for 5h; Heating / reflux;

upstream raw materials:

3,3'-Iminodipropionitrile

benzyl chloride

iodomethylbenzene

acrylonitrile

Downstream raw materials:

N1-(3-amino-propyl)-N1-benzyl-propane-1,3-diamine

N,N-bis(3-(N,N-bis(3-aminopropyl)amino)propyl)benzylamine

3-[[3-(benzyl-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-(2-cyano-ethyl)-amino]-propionitrile

4-amino-1-benzyl-1.2.5.6-tetrahydropyridine-3-carbonitrile

Refernces

• 1、 Gopiraman, Mayakrishnan,Saravanamoorthy, Somasundaram,Baskar, Ramaganthan,Ilangovan, Andivelu,Ill-Min, Chung. "Green synthesis of Ag@Au bimetallic regenerated cellulose nanofibers for catalytic applications". . p. 17090 - 17103. Retrieved 2019/11/14.
• 2、 -. "3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF". Paragraph 00337. . Retrieved 2017/09/27.