2-(2-AMINOETHYL)BENZOIC ACID HYDROCHLORIDE

Base Information

• Chemical Name: 2-(2-AMINOETHYL)BENZOIC ACID HYDROCHLORIDE
• CAS No.: 102879-42-5
• Molecular Formula: C₉H₁₁NO₂*ClH
• Molecular Weight: 201.653
• Hs Code.: 2922499990
• Mol file: 102879-42-5.mol

Synonyms:Benzoicacid,2-(2-aminoethyl)-,hydrochloride (9CI);Benzoic acid,o-(2-aminoethyl)-,hydrochloride (6CI);2-(Aminoethyl)-benzoic acid hydrochloride;

Chemical Property of 2-(2-AMINOETHYL)BENZOIC ACID HYDROCHLORIDE

Chemical Property:

• PSA: 63.32000
• LogP: 2.38830
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

2-(2-Aminoethyl)benzoicAcidHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-AMINOETHYL)BENZOIC ACID HYDROCHLORIDE

There total 3 articles about 2-(2-AMINOETHYL)BENZOIC ACID HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

3,4-dihydroisoquinolin-1(2H)-one (1196-38-9) → 2-(2-aminoethyl)benzoic acid hydrochloride salt (102879-42-5)

Guidance literature:

With hydrogenchloride; at 165 ℃; for 42h;

DOI:10.1039/b108179a

Reference yield:

inden-1-one (83-33-0) → 2-(2-aminoethyl)benzoic acid hydrochloride salt (102879-42-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride; sodium azide / water / 20 °C

2: hydrogenchloride; water / 110 °C / Sealed tube

With hydrogenchloride; sodium azide; water; In water;

DOI:10.1002/cmdc.202100699

Reference yield:

→ 2-(2-aminoethyl)benzoic acid hydrochloride salt (102879-42-5)

Guidance literature:

With hydrogenchloride; at 150 - 160 ℃; im geschlossenen Rohr;

upstream raw materials:

3,4-dihydroisoquinolin-1(2H)-one

inden-1-one

Refernces

• 1、 Clark,Hodgson,Goldsmith,Street. "Rearrangement of ammonium ylides produced by intramolecular reaction of catalytically generated metal carbenoids. Part 1. Synthesis of cyclic amines". . p. 3312 - 3324. Retrieved 2007/10/03.