Propane-1-sulfonamide

Base Information

• Chemical Name: Propane-1-sulfonamide
• CAS No.: 24243-71-8
• Molecular Formula: C3H9NO2S
• Molecular Weight: 123.176
• Hs Code.: 2935009090
• European Community (EC) Number: 696-085-2
• DSSTox Substance ID: DTXSID40392158
• Wikidata: Q72502257
• Mol file: 24243-71-8.mol

Synonyms:Propane-1-sulfonamide;24243-71-8;Propanesulfonamide;Propane-1-sulphonamide;1-Propanesulfonamide;MFCD03550611;n-propanesulphonamide;Propansulfonamid;propanesulphonamide;n-propylsulfonamide;SCHEMBL28097;DTXSID40392158;DROIHSMGGKKIJT-UHFFFAOYSA-N;AMY27802;BCP20038;STR06425;ZAA24371;BBL102753;STL556559;AKOS000146817;CS-W022937;SB75389;FT-0746133;EN300-77788;W12497;J-015411

Chemical Property of Propane-1-sulfonamide

Chemical Property:

• Vapor Pressure: 0.0805mmHg at 25°C
• Melting Point: 51-52 °C
• Refractive Index: 1.464
• Boiling Point: 226.7 °C at 760 mmHg
• PKA: 10.87±0.60(Predicted)
• Flash Point: 90.9 °C
• PSA: 68.54000
• Density: 1.198 g/cm³
• LogP: 1.46600
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 123.03539970
• Heavy Atom Count: 7
• Complexity: 120

Purity/Quality:

98%,99%, ^*data from raw suppliers

Propane-1-sulfonamide(~90%) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCS(=O)(=O)N
• Uses: Propylsulfonamide is used in the preparation of different electron donors in luminogenic luciferins and fluorescent dyes.

Technology Process of Propane-1-sulfonamide

There total 4 articles about Propane-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

n-propanesulfonyl chloride (10147-36-1) → propane-1-sulfonamide (24243-71-8)

Guidance literature:

With ammonia; In diethyl ether; at 0 ℃; for 0.166667h;

Reference yield: 88.0%

→ propane-1-sulfonamide (24243-71-8)

Guidance literature:

Reference yield: 6.0%

1,3-propanesultone (1120-71-4) → propane-1-sulfonamide (24243-71-8)

Guidance literature:

multistep reaction;

DOI:10.1021/jo00314a022

upstream raw materials:

n-propanesulfonyl chloride

1,3-propanesultone

Refernces

• 1、 -. "PATTERN FORMING METHOD, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, MANUFACTURING METHOD OF ELECTRONIC DEVICE, ELECTRONIC DEVICE AND COMPOUND". . . Retrieved 2016/04/20.
• 2、 -. "PYRAZINE DERIVATIVES AND USE AS PI3K INHIBITORS". Page/Page column 40. . Retrieved 2008/06/13.