1,1,3,3-Tetramethoxybutane

Base Information

• Chemical Name: 1,1,3,3-Tetramethoxybutane
• CAS No.: 5744-65-0
• Molecular Formula: C8H18O4
• Molecular Weight: 178.229
• DSSTox Substance ID: DTXSID30354785
• Nikkaji Number: J1.567.113K
• Wikidata: Q72507437
• Mol file: 5744-65-0.mol

Synonyms:1,1,3,3-tetramethoxybutane;5744-65-0;C8H18O4;SCHEMBL4195938;DTXSID30354785;5,7-Dichloroindole-2-carboxylicAcid;AKOS006343524;CS-0278859;FT-0653368;EN300-312461;A831444

Chemical Property of 1,1,3,3-Tetramethoxybutane

Chemical Property:

• Boiling Point: 194.1 °C at 760 mmHg
• Flash Point: 67.1 °C
• PSA: 36.92000
• Density: 0.955 g/cm³
• LogP: 1.00440
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 178.12050905
• Heavy Atom Count: 12
• Complexity: 108

Purity/Quality:

98.00% ^*data from raw suppliers

1,1,3,3-tetramethoxybutane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CC(OC)OC)(OC)OC

Technology Process of 1,1,3,3-Tetramethoxybutane

There total 5 articles about 1,1,3,3-Tetramethoxybutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

acetylacetaldehyde dimethyl acetal (5436-21-5) + trimethyl orthoformate (149-73-5) → 1,1,3,3-tetramethoxy-butane (5744-65-0)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; at 20 ℃; for 24h;

DOI:10.1016/j.tetlet.2009.01.005

Reference yield:

methanol (67-56-1) + 1-methoxy-buten-3-yne (2798-73-4) → 1,1,3,3-tetramethoxy-butane (5744-65-0)

Guidance literature:

With mercury(II) sulfate;

Reference yield:

Trimethyl orthoacetate (1445-45-0) + methoxyethene (107-25-5,9003-09-2) → 1,1,3,3-tetramethoxy-butane (5744-65-0)

Guidance literature:

With tin(IV) chloride;

upstream raw materials:

methanol

1-methoxy-buten-3-yne

Trimethyl orthoacetate

methoxyethene

Downstream raw materials:

4-methyl-pyrimidine-2-thione

1,3,5-triacetylbenzene

acetylacetaldehyde dimethyl acetal

2-hydroxy-6-methylnicotinonitrile

Refernces