Sulfuric acid mono-((S)-2-oxo-3-phenylacetylamino-azetidin-1-yl) ester; compound with pyridine

Base Information

• Chemical Name: Sulfuric acid mono-((S)-2-oxo-3-phenylacetylamino-azetidin-1-yl) ester; compound with pyridine
• CAS No.: 82933-27-5
• Molecular Formula: C₅H₅N*C₁₁H₁₂N₂O₆S
• Molecular Weight: 379.393
• Mol file: 82933-27-5.mol

Synonyms:Sulfuric acid mono-((S)-2-oxo-3-phenylacetylamino-azetidin-1-yl) ester; compound with pyridine

Chemical Property of Sulfuric acid mono-((S)-2-oxo-3-phenylacetylamino-azetidin-1-yl) ester; compound with pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

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Useful:

Technology Process of Sulfuric acid mono-((S)-2-oxo-3-phenylacetylamino-azetidin-1-yl) ester; compound with pyridine

There total 2 articles about Sulfuric acid mono-((S)-2-oxo-3-phenylacetylamino-azetidin-1-yl) ester; compound with pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

sulfur trioxide pyridine complex (26412-87-3) + (S)-N-(1-Hydroxy-2-oxo-3-azetidinyl)-2-phenylacetamide (82933-25-3) → Sulfuric acid mono-((S)-2-oxo-3-phenylacetylamino-azetidin-1-yl) ester; compound with pyridine (82933-27-5)

Guidance literature:

With pyridine; at 26 ℃; for 2h;

DOI:10.1021/ja00386a035

Reference yield:

1-(benzyloxy)-3-((phenylacetyl)amino)-2-azetidinone (75624-37-2) → Sulfuric acid mono-((S)-2-oxo-3-phenylacetylamino-azetidin-1-yl) ester; compound with pyridine (82933-27-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / hydrogen / 10percent Pd/C / ethanol / 1 h / 26 °C

2: 43 percent / pyridine / 2 h / 26 °C

With pyridine; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1021/ja00386a035

Reference yield: 100.0%

Sulfuric acid mono-((S)-2-oxo-3-phenylacetylamino-azetidin-1-yl) ester; compound with pyridine (82933-27-5) → C11H11N2O6S(1-)*K(1+) (82933-28-6)

Guidance literature:

With Dowex W₂ ion-exchange resin (K+ form); In water;

DOI:10.1021/ja00386a035

upstream raw materials:

sulfur trioxide pyridine complex

(S)-N-(1-Hydroxy-2-oxo-3-azetidinyl)-2-phenylacetamide

1-(benzyloxy)-3-((phenylacetyl)amino)-2-azetidinone

Downstream raw materials:

C₁₁H₁₁N₂O₆S^(1-)*K⁽¹⁺⁾

Refernces