2-Bromoethylamine

Base Information

• Chemical Name: 2-Bromoethylamine
• CAS No.: 107-09-5
• Molecular Formula: C2H6 Br N
• Molecular Weight: 123.98
• Hs Code.: 2921199090
• European Community (EC) Number: 203-461-8
• DSSTox Substance ID: DTXSID8059346
• Nikkaji Number: J75.054I
• Wikidata: Q81988768
• ChEMBL ID: CHEMBL1697693
• Mol file: 107-09-5.mol

Synonyms:2-BEA;2-bromoethanamine;2-bromoethanamine hydrobromide;2-bromoethylamine;2-bromoethylamine hydrobromide;bromoethyleneamine hydrobromide

Chemical Property of 2-Bromoethylamine

Chemical Property:

• Vapor Pressure: 9.12mmHg at 25°C
• Refractive Index: 1.4800 (estimate)
• Boiling Point: 131.8°Cat760mmHg
• PKA: 7.75±0.10(Predicted)
• Flash Point: 33.5°C
• PSA: 26.02000
• Density: 1.581g/cm³
• LogP: 1.04030
• XLogP3: 0
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 122.96836
• Heavy Atom Count: 4
• Complexity: 10

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-BROMOETHYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic
• Canonical SMILES: C(CBr)N

Technology Process of 2-Bromoethylamine

There total 13 articles about 2-Bromoethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-(3-Hydroxypropyl)-4-(2'-hydroxyethylamino)phthalazin-1(2H)-one (133056-80-1) → 2-bromoethylamine (107-09-5) + 2,3-Dihydro-1H-pyrazolo<1,2-b>phthalazin-5,10(4H,11H)-dione (21769-81-3)

Guidance literature:

With hydrogen bromide; for 0.0833333h; Heating;

DOI:10.1016/S0040-4020(01)87114-3

Reference yield:

N-(2-bromoethyl)phthalimic acid (98945-49-4) → 2-bromoethylamine (107-09-5) + benzene-1,2-dicarboxylic acid (88-99-3,73607-73-5)

Guidance literature:

With sodium hydroxide; potassium chloride; at 25 ℃; for 0.166667h; Mechanism;

DOI:10.1021/jo00350a082

Reference yield:

2-(2-bromoethyl)isoindoline-1,3-dione (574-98-1) + hydrogen bromide (10035-10-6,12258-64-9) → 2-bromoethylamine (107-09-5) + benzene-1,2-dicarboxylic acid (88-99-3,73607-73-5)

Guidance literature:

at 180 - 200 ℃;

upstream raw materials:

ethyleneimine

2-(2-bromoethyl)isoindoline-1,3-dione

aziridine; hydrobromide

ethanolamine

Downstream raw materials:

2-(N,N-dimethylamino)ethyl bromide

2,5-bis-(2-bromo-ethylamino)-terephthalic acid diethyl ester

4-methoxy-3-nitro-benzoic acid-(2-bromo-ethylamide)

2-propylsulfanylethylamine

Refernces

• 1、 -. "Aminopolycarboxylic acid-series chelating agent, heavy metal compound thereof, photographic additive, and processing method". . . Retrieved 2008/06/13.
• 2、 Csampai,Kormendy,Ruff. "Chain length dependent reactivity of 2-(ω-hydroxyalkyl)-4-(ω'-hydroxyalkylamino)phthalazin-1(2H)-ones in azeotropic hydrobromic acid". . p. 4457 - 4464. Retrieved 2007/10/02.