Technology Process of 5-(1-Hexyl-cyclopentyl)-2-((1R,6R)-6-isopropenyl-3-methyl-cyclohex-2-enyl)-benzene-1,3-diol
There total 7 articles about 5-(1-Hexyl-cyclopentyl)-2-((1R,6R)-6-isopropenyl-3-methyl-cyclohex-2-enyl)-benzene-1,3-diol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
benzene;
at 10 - 20 ℃;
for 1h;
DOI:10.1021/jm020558c
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 96 percent / tetrahydrofuran / 0.75 h / 10 °C
2: 95 percent / H2 / Pd/C / ethyl acetate / 20 °C
3: 90 percent / BBr3 / CH2Cl2 / 120 h / -20 °C
4: 85 percent / p-toluenesulfonic acid / benzene / 1 h / 10 - 20 °C
With
hydrogen; boron tribromide; toluene-4-sulfonic acid;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane; ethyl acetate; benzene;
1: Wittig olefination;
DOI:10.1021/jm020558c
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium bis(trimethylsilyl)amide / tetrahydrofuran / 30 h / 10 °C
2: 96 percent / tetrahydrofuran / 0.75 h / 10 °C
3: 95 percent / H2 / Pd/C / ethyl acetate / 20 °C
4: 90 percent / BBr3 / CH2Cl2 / 120 h / -20 °C
5: 85 percent / p-toluenesulfonic acid / benzene / 1 h / 10 - 20 °C
With
hydrogen; boron tribromide; potassium hexamethylsilazane; toluene-4-sulfonic acid;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane; ethyl acetate; benzene;
2: Wittig olefination;
DOI:10.1021/jm020558c