l-Propoxyphene

Base Information

• Chemical Name: l-Propoxyphene
• CAS No.: 77-50-9
• Deprecated CAS: 8059-45-8
• Molecular Formula: C₂₂H₂₉NO₂
• Molecular Weight: 339.478
• DSSTox Substance ID: DTXSID60859379
• Nikkaji Number: J55.484G
• Wikidata: Q23766565
• Pharos Ligand ID: VYH156NNMHBU
• ChEMBL ID: CHEMBL300117
• Mol file: 77-50-9.mol

Synonyms:77-50-9;Propoxyphene, dl-;CHEBI:77401;1,2-Diphenyl-2-propionoxy-3-methyl-4-dimethylaminobutane;4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-butanol propionate;alpha-4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanolpropionate;alpha-4-Dimethylamino-1,2-diphenyl-3-methyl-4-propionyloxybutane;alpha-N,N-Dimethyl-3,4-diphenyl-2-methyl-3-propionoxy-1-butylamine;1,2-Difenyl-4-dimethylamino-3-methyl-2-butylester kyseliny propionove [Czech];2-BUTANOL, 4-(DIMETHYLAMINO)-3-METHYL-1,2-DIPHENYL-, PROPIONATE (ester);Benzeneethanol, alpha-(2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester);Propionic acid, alpha-(2-dimethylamino-1-methylethyl)-alpha-phenylphenethyl ester;Levo-Propoxyphene;(1R,2S)-1-Benzyl-3-dimethylamino-2-methyl-1-phenylpropyl propionate;1,2-Difenyl-4-dimethylamino-3-methyl-2-butylester kyseliny propionove;Benzeneethanol, .alpha.-[2-(dimethylamino)-1-methylethyl]-.alpha.-phenyl-, propanoate (ester);Levopropoxyphen;DL-propoxyphene;Propoxyphenhydrochlorid;[4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl] propanoate;SCHEMBL25406;1-Benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propionate #;CHEMBL300117;DTXSID60859379;Benzeneethanol, .alpha.-[2-(dimethylamino)-1-methylethyl]-.alpha.-phenyl-, propanoate (ester), [S-(R*,S*)]-;Benzeneethanol, alpha-((1S)-2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester), (alphaR)-;Benzeneethanol, alpha-(2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester), (R-(R*,S*))-;PDSP1_001243;PDSP2_001227;Propoxyphene, (R-(R*,S*))-Isomer;LS-46518;LS-173995;AB00514748;L001219;Q23766565;4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl propanoate;Propionic acid 3-(dimethylamino)-2-methyl-1-phenyl-1-benzylpropyl ester

Chemical Property of l-Propoxyphene

Chemical Property:

• Melting Point: 75.5°C
• Refractive Index: 1.5614 (estimate)
• Boiling Point: 475.43°C (rough estimate)
• PSA: 29.54000
• Density: 1.0751 (rough estimate)
• LogP: 4.27550
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 9
• Exact Mass: 339.219829168
• Heavy Atom Count: 25
• Complexity: 397

Purity/Quality:

99%, ^*data from raw suppliers

BENZENEETHANOL, ALPHA-2-(DIMETHYLAMINO)-1-METHYLETHYL-ALPHA-PHENYL-, PROPANOATE (ESTER) 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 3
• Hazard Codes: 3

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(=O)OC(CC1=CC=CC=C1)(C2=CC=CC=C2)C(C)CN(C)C

Technology Process of l-Propoxyphene

There total 1 articles about l-Propoxyphene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ dextropropoxyphene (77-50-9,21086-94-2,3818-94-8,8059-45-8)

Guidance literature:

durch Ionenpaarextraktion m. CH2Cl2 in Anwesenheit von Bromthymol Blau;