N,N-dimethyl-3,4-dimethoxyphenylglyoxamide

Base Information

• Chemical Name: N,N-dimethyl-3,4-dimethoxyphenylglyoxamide
• CAS No.: 127901-47-7
• Molecular Formula: C₁₂H₁₅NO₄
• Molecular Weight: 237.255
• Mol file: 127901-47-7.mol

Synonyms:N,N-dimethyl-3,4-dimethoxyphenylglyoxamide

Chemical Property of N,N-dimethyl-3,4-dimethoxyphenylglyoxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-dimethyl-3,4-dimethoxyphenylglyoxamide

There total 3 articles about N,N-dimethyl-3,4-dimethoxyphenylglyoxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-dimethoxybenzene (91-16-7) → N,N-dimethyl-3,4-dimethoxyphenylglyoxamide (127901-47-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 42 percent / p-toluenesulfonic acid / 1,2-dichloro-ethane / 1 h / Heating

2: sodium metaperiodate / H₂O; methanol / 15 h / Ambient temperature

3: acetic anhydride / 0.5 h / Heating

With sodium periodate; acetic anhydride; toluene-4-sulfonic acid; In methanol; water; 1,2-dichloro-ethane;

DOI:10.1248/cpb.37.3396

Reference yield:

2-(3,4-Dimethoxy-phenyl)-N,N-dimethyl-2-methylsulfanyl-acetamide (127901-39-7) → N,N-dimethyl-3,4-dimethoxyphenylglyoxamide (127901-47-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium metaperiodate / H₂O; methanol / 15 h / Ambient temperature

2: acetic anhydride / 0.5 h / Heating

With sodium periodate; acetic anhydride; In methanol; water;

DOI:10.1248/cpb.37.3396

Reference yield:

2-(3,4-Dimethoxy-phenyl)-2-methanesulfinyl-N,N-dimethyl-acetamide (127901-45-5) → N,N-dimethyl-3,4-dimethoxyphenylglyoxamide (127901-47-7)

Guidance literature:

With acetic anhydride; for 0.5h; Yield given; Heating;

DOI:10.1248/cpb.37.3396

upstream raw materials:

2-(3,4-Dimethoxy-phenyl)-2-methanesulfinyl-N,N-dimethyl-acetamide

1,2-dimethoxybenzene

2-(3,4-Dimethoxy-phenyl)-N,N-dimethyl-2-methylsulfanyl-acetamide

Downstream raw materials:

1-(3, 4-dimethoxyphenyl)-2-dimethylaminoethanol

Refernces