Me₄H(2,2)TIAM

Base Information

• Chemical Name: Me₄H(2,2)TIAM
• CAS No.: 872705-82-3
• Molecular Formula: C₅₈H₇₆N₁₄O₁₆
• Molecular Weight: 1225.33
• Mol file: 872705-82-3.mol

Synonyms:Me₄H(2,2)TIAM

Chemical Property of Me₄H(2,2)TIAM

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Me₄H(2,2)TIAM

There total 8 articles about Me₄H(2,2)TIAM which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-methoxy-N1,N3-dimethyl-5-(2-thioxothiazolidine-3-carbonyl)isophthalamide (872705-77-6) + ethylenediamine (107-15-3,85404-18-8) → Me4H(2,2)TIAM (872705-82-3)

Guidance literature:

In dichloromethane;

Reference yield: 77.0%

4-methoxy-N1,N3-dimethyl-5-(2-thioxothiazolidine-3-carbonyl)isophthalamide (872705-77-6) + N,N,N',N'-tetrakis-(2-aminoethyl)ethylenediamine (4097-90-9) → Me4H(2,2)TIAM (872705-82-3)

Guidance literature:

In dichloromethane;

DOI:10.1002/anie.201106748

Reference yield:

2,6-bis(hydroxymethyl)-4-methylphenol (91-04-3) → Me4H(2,2)TIAM (872705-82-3)

Guidance literature:

Multi-step reaction with 7 steps

1: sodium hydroxide / water

2: potassium permanganate; sodium hydroxide / water / 20 - 90 °C

3: thionyl chloride; N,N-dimethyl-formamide / 1,4-dioxane / Reflux; Inert atmosphere

4: triethylamine / dichloromethane

5: dichloromethane; water; isopropyl alcohol / 48 h

6: dichloromethane; water; isopropyl alcohol / 48 h

7: dichloromethane

With potassium permanganate; thionyl chloride; triethylamine; N,N-dimethyl-formamide; sodium hydroxide; In 1,4-dioxane; dichloromethane; water; isopropyl alcohol;

DOI:10.1002/anie.201106748

upstream raw materials:

4-methoxy-N₁,N₃-dimethyl-5-(2-thioxothiazolidine-3-carbonyl)isophthalamide

ethylenediamine

2,6-bis(hydroxymethyl)-4-methylphenol

1-methoxy-2,4,6-benzenetricarbonyl trichloride

Refernces

• 1、 -. "AROMATIC TRIAMIDE-LANTHANIDE COMPLEXES". Page/Page column 78-79. . Retrieved 2008/06/13.