1,2-Bis(dimethylsilyl)ethane

Base Information

• Chemical Name: 1,2-Bis(dimethylsilyl)ethane
• CAS No.: 20152-11-8
• Molecular Formula: C6H18Si2
• Molecular Weight: 146.38
• Hs Code.: 2931900090
• European Community (EC) Number: 683-392-1
• Mol file: 20152-11-8.mol

Synonyms:20152-11-8;1,2-bis(dimethylsilyl)ethane;1,1,4,4-Tetramethyl-1,4-disilabutane;1,1,4,4-TETRAMETHYLDISILETHYLENE;1,2-BIS(DIMETHYLSILYL)ETHANE (D6);MFCD00053847;FT-0647470;1,1,4,4-Tetramethyldisilethylene(Bis dimethylsilyl ethane);3-(4-HYDROXY-2-METHYL-QUINOLIN-3-YL)-PROPIONICACID

Chemical Property of 1,2-Bis(dimethylsilyl)ethane

Chemical Property:

• Vapor Pressure: 20.1mmHg at 25°C
• Refractive Index: n20/D 1.421
• Boiling Point: 118.2 °C at 760 mmHg
• Flash Point: 16.3 °C
• PSA: 0.00000
• Density: 0.743
• LogP: 1.95980
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 144.07905358
• Heavy Atom Count: 8
• Complexity: 42.5

Purity/Quality:

98% ^*data from raw suppliers

1,1,4,4-TETRAMETHYLDISILETHYLENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,Xi
• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 9-16-33-36-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)CC[Si](C)C

Technology Process of 1,2-Bis(dimethylsilyl)ethane

There total 2 articles about 1,2-Bis(dimethylsilyl)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1,2-bis-(chlorodimethylsilyl)ethane (13528-93-3) → 1,2-bis(dimethylsilyl)ethane (20152-11-8)

Guidance literature:

With lithium aluminium tetrahydride; at 0 - 50 ℃; for 5h; Inert atmosphere;

DOI:10.1039/c8cc01163j

Reference yield: 16.0%

1,2-bis-(chlorodimethylsilyl)ethane (13528-93-3) → 1,2-bis(dimethylsilyl)ethane (20152-11-8) + <2-(chlorodimethylsilyl)ethyl>dimethylsilane (76490-68-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 3h; Heating;

DOI:10.1016/0022-328X(89)85001-6

Reference yield: 95.0%

3,5,5-Trimethylcyclohex-2-en-1-one (78-59-1) + 1,2-bis(dimethylsilyl)ethane (20152-11-8) → 1-[(2-Dimethylsilanyl-ethyl)-dimethyl-silanyloxy]-5,5-dimethyl-3-methylene-cyclohexene

Guidance literature:

With RhCl₃(iPr-Pybox); silver trifluoromethanesulfonate; In dichloromethane; at 40 - 50 ℃; for 4.5h;

DOI:10.1246/cl.1993.347

upstream raw materials:

1,2-bis-(chlorodimethylsilyl)ethane

Downstream raw materials:

1,1,4,4-tetramethyl-5,6-diphenyl-1,2,3,4-tetrahydro-[1,4]disiline

1-(4-bromophenyl)-2,2,5,5-tetramethyl-1,2,5-azadisilolidine

cis,mer-{RhH₂(SPh)(PMe₃)3}

[RuH2[(η(2)-HSiMe2)2(CH2)2](PCy3)2]

Refernces

• 1、 Xie, Hengmu,Lu, Ji,Gui, Yingying,Gao, Lu,Song, Zhenlei. "(HMe 2 SiCH 2) 2: A Useful Reagent for B(C 6 F 5) 3 -Catalyzed Reduction-Lactonization of Keto Acids: Concise Syntheses of (-)- cis -Whisky and (-)- cis -Cognac Lactones". supporting information. p. 2453 - 2459. Retrieved 2017/10/06.
• 2、 Hanada, Shiori,Motoyama, Yukihiro,Nagashima, Hideo. "Hydrosilanes are not always reducing agents for carbonyl compounds but can also induce dehydration: A ruthenium-catalyzed conversion of primary amides to nitriles". supporting information; experimental part. p. 4097 - 4100. Retrieved 2009/04/10.